Source:http://linkedlifedata.com/resource/pubmed/id/20562445
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2010-8-18
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pubmed:abstractText |
Bilirubin, an effective antioxidant, shows a large variation in levels between individuals and has been positively associated with reduced cardiovascular disease risk. A major reason for the variability is a common promoter polymorphism, UGT1A1*28, which reduces the transcription of the enzyme that conjugates bilirubin, UDP-glucuronosyltransferase 1A1. The aim of the study was to evaluate a possible protective effect of plasma bilirubin and the UGT1A1*28 polymorphism against myocardial infarction in a prospective case-referent setting.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1942-3268
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
3
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
340-7
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pubmed:dateRevised |
2011-3-21
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pubmed:meshHeading |
pubmed-meshheading:20562445-Adult,
pubmed-meshheading:20562445-Age of Onset,
pubmed-meshheading:20562445-Aged,
pubmed-meshheading:20562445-Bilirubin,
pubmed-meshheading:20562445-Case-Control Studies,
pubmed-meshheading:20562445-Cohort Studies,
pubmed-meshheading:20562445-Cytoprotection,
pubmed-meshheading:20562445-Female,
pubmed-meshheading:20562445-Gene Dosage,
pubmed-meshheading:20562445-Glucuronosyltransferase,
pubmed-meshheading:20562445-Humans,
pubmed-meshheading:20562445-Male,
pubmed-meshheading:20562445-Middle Aged,
pubmed-meshheading:20562445-Myocardial Infarction,
pubmed-meshheading:20562445-Polymorphism, Genetic,
pubmed-meshheading:20562445-Prospective Studies
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pubmed:year |
2010
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pubmed:articleTitle |
Plasma bilirubin and UGT1A1*28 are not protective factors against first-time myocardial infarction in a prospective, nested case-referent setting.
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pubmed:affiliation |
Clinical Chemistry, Department of Medical Biosciences, Umeå University, Umeå Sweden. kim.ekblom@medbio.umu.se
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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