Source:http://linkedlifedata.com/resource/pubmed/id/20560858
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2011-3-16
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pubmed:abstractText |
The anti-hyperglycaemic effects of the leaves of Acer pycnanthum K. Koch, and the purification and identification of the active compounds were investigated. Extracts of the leaves showed a potent inhibitory effect on the ?-glucosidase in both in vivo and in vitro experiments. The fractionation of the crude extract gave two active compounds, ginnalin B (6-O-galloyl-1,5-anhydro-D-glucitol) and ginnalin C (2-O-galloyl-1,5-anhydro-D-glucitol), by spectroscopic analysis. This is the first report that A. pycnanthum and its constituents may be useful for the prevention or treatment of diabetes mellitus.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Hypoglycemic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Plant Extracts,
http://linkedlifedata.com/resource/pubmed/chemical/Sorbitol,
http://linkedlifedata.com/resource/pubmed/chemical/Sucrase
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1475-6374
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
176-80
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pubmed:meshHeading |
pubmed-meshheading:20560858-Acer,
pubmed-meshheading:20560858-Animals,
pubmed-meshheading:20560858-Enzyme Activation,
pubmed-meshheading:20560858-Enzyme Inhibitors,
pubmed-meshheading:20560858-Hypoglycemic Agents,
pubmed-meshheading:20560858-Kinetics,
pubmed-meshheading:20560858-Male,
pubmed-meshheading:20560858-Mice,
pubmed-meshheading:20560858-Plant Extracts,
pubmed-meshheading:20560858-Plant Leaves,
pubmed-meshheading:20560858-Sorbitol,
pubmed-meshheading:20560858-Sucrase
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pubmed:year |
2011
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pubmed:articleTitle |
Anti-hyperglycaemic effects of the Japanese red maple Acer pycnanthum and its constituents the ginnalins B and C.
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pubmed:affiliation |
Laboratory of Nutraceuticals and Functional Foods Science, Graduate School of Marine Science and Technology, Tokyo University of Marine Science and Technology, 4-5-7 Konan, Minato-ku, Tokyo 108-8477, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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