Linked Life Data

20558065

Source:http://linkedlifedata.com/resource/pubmed/id/20558065

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2010-8-3
pubmed:abstractText
Mechanical ventilation has improved survival in patients with Duchenne muscular dystrophy (DMD). Over time, these patients experience upper airway dysfunction, swallowing impairments, and dependency on the ventilator that may require invasive mechanical ventilation via a tracheostomy. Tracheostomy is traditionally believed to further impair swallowing. We assessed swallowing performance and breathing-swallowing interactions before and after tracheostomy in 7 consecutive wheelchair-bound DMD patients, aged 25+/-4 years, over a 4-year period. Chin electromyography, laryngeal motion, and inductive respiratory plethysmography recordings were obtained during swallowing of three water-bolus sizes in random order. Piecemeal deglutition occurred in all patients over several breathing cycles. Half the swallows were followed by inspiration before tracheostomy. Total bolus swallowing time was significantly shorter (P=0.009), and the number of swallows per bolus significantly smaller (P=0.01), after than before tracheostomy. Invasive ventilation via a tracheostomy may improve swallowing.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1873-2364
pubmed:author
pubmed:copyrightInfo
2010 Elsevier B.V. All rights reserved.
pubmed:issnType
Electronic
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
493-8
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Impact of tracheostomy on swallowing performance in Duchenne muscular dystrophy.
pubmed:affiliation
Service de Réanimation Médicale, CHU de Caen, 14000 Caen, France. terzi-n@chu-caen.fr
pubmed:publicationType
Journal Article, Clinical Trial, Research Support, Non-U.S. Gov't