20553946

Source:http://linkedlifedata.com/resource/pubmed/id/20553946

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0002313, umls-concept:C0003440, umls-concept:C0313529, umls-concept:C1883254
pubmed:issue	3
pubmed:dateCreated	2010-8-30
pubmed:abstractText	A mannogalactan from Pleurotus ostreatoroseus (MgPr) was chemically sulfated to give MgPr-S1, which was evaluated for its anticoagulant and antithrombotic activities, bleeding tendency, and platelet aggregation.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0326377
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Anticoagulants, http://linkedlifedata.com/resource/pubmed/chemical/Antithrombin Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Factor Xa, http://linkedlifedata.com/resource/pubmed/chemical/Fibrinolytic Agents, http://linkedlifedata.com/resource/pubmed/chemical/Galactans, http://linkedlifedata.com/resource/pubmed/chemical/Heparin Cofactor II, http://linkedlifedata.com/resource/pubmed/chemical/Sulfates, http://linkedlifedata.com/resource/pubmed/chemical/Thrombin
pubmed:status	MEDLINE
pubmed:month	Sep
pubmed:issn	1879-2472
pubmed:author	pubmed-author:CarboneroElaine RER, pubmed-author:CiprianiThales RTR, pubmed-author:GorinPhilip A JPA, pubmed-author:GracherAna Helena PAH, pubmed-author:IacominiMarcelloM
pubmed:copyrightInfo	Copyright (c) 2010 Elsevier Ltd. All rights reserved.
pubmed:issnType	Electronic
pubmed:volume	126
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	e180-7
pubmed:meshHeading	pubmed-meshheading:20553946-Animals, pubmed-meshheading:20553946-Anticoagulants, pubmed-meshheading:20553946-Antithrombin Proteins, pubmed-meshheading:20553946-Bleeding Time, pubmed-meshheading:20553946-Blood Coagulation, pubmed-meshheading:20553946-Chromatography, Gel, pubmed-meshheading:20553946-Disease Models, Animal, pubmed-meshheading:20553946-Dose-Response Relationship, Drug, pubmed-meshheading:20553946-Factor Xa, pubmed-meshheading:20553946-Female, pubmed-meshheading:20553946-Fibrinolytic Agents, pubmed-meshheading:20553946-Galactans, pubmed-meshheading:20553946-Hemorrhage, pubmed-meshheading:20553946-Heparin Cofactor II, pubmed-meshheading:20553946-Humans, pubmed-meshheading:20553946-Magnetic Resonance Spectroscopy, pubmed-meshheading:20553946-Male, pubmed-meshheading:20553946-Partial Thromboplastin Time, pubmed-meshheading:20553946-Platelet Aggregation, pubmed-meshheading:20553946-Pleurotus, pubmed-meshheading:20553946-Prothrombin Time, pubmed-meshheading:20553946-Rats, pubmed-meshheading:20553946-Rats, Wistar, pubmed-meshheading:20553946-Scattering, Radiation, pubmed-meshheading:20553946-Structure-Activity Relationship, pubmed-meshheading:20553946-Sulfates, pubmed-meshheading:20553946-Thrombin, pubmed-meshheading:20553946-Venous Thrombosis
pubmed:year	2010
pubmed:articleTitle	Antithrombin and heparin cofactor II-mediated inactivation of alpha-thrombin by a synthetic, sulfated mannogalactan.
pubmed:affiliation	Laboratório de Química de Carboidratos, Departamento de Bioquímica e Biologia Molecular, Universidade Federal do Paraná, Curitiba, Paraná, Brazil.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't