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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2010-10-28
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pubmed:abstractText |
The metabolism of estrogen contained within hormone replacement therapy (HRT) is influenced by the route of administration, and this may affect the risk of venous thromboembolism. Thrombin generation, a global coagulation assay, is a marker of hypercoagulability and is of potential use in determining the thrombotic risk associated with particular HRT administration routes.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1538-7836
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pubmed:author |
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pubmed:copyrightInfo |
© 2010 International Society on Thrombosis and Haemostasis.
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pubmed:issnType |
Electronic
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1736-44
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pubmed:meshHeading |
pubmed-meshheading:20553380-Administration, Cutaneous,
pubmed-meshheading:20553380-Administration, Oral,
pubmed-meshheading:20553380-Case-Control Studies,
pubmed-meshheading:20553380-Estradiol,
pubmed-meshheading:20553380-Estrogen Replacement Therapy,
pubmed-meshheading:20553380-Estrogens,
pubmed-meshheading:20553380-Estrone,
pubmed-meshheading:20553380-Female,
pubmed-meshheading:20553380-Hormone Replacement Therapy,
pubmed-meshheading:20553380-Humans,
pubmed-meshheading:20553380-Reproducibility of Results,
pubmed-meshheading:20553380-Risk,
pubmed-meshheading:20553380-Thrombin,
pubmed-meshheading:20553380-Thrombosis
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pubmed:year |
2010
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pubmed:articleTitle |
The effect of estrone on thrombin generation may explain the different thrombotic risk between oral and transdermal hormone replacement therapy.
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pubmed:affiliation |
King's Thrombosis Centre, King's College Hospital NHS Foundation Trust, London, UK. catherine.bagot@ggc.scot.nhs.uk
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pubmed:publicationType |
Journal Article
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