Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1991-7-31
pubmed:abstractText
Neuropeptide Y (NPY) (50-1000 nM) failed to modify basal or K(+)-stimulated Ca2+ influx in cortical or hippocampal synaptosomes from rat brain, whereas the voltage-sensitive Ca2+ channel (VSCC) blocker Cd2+ (50 microM) caused major inhibition. In cortical synaptosomes from chicken brain NPY (1.0 microM) failed to modify, whereas omega-conotoxin GV1A (0.1 microM) markedly inhibited Ca2+ influx. NPY does not appear to modify synaptosomal Ca2+ influx, however it may still affect VSCCs spatially distinct or 'upstream' from the nerve terminals.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0014-2999
pubmed:author
pubmed:issnType
Print
pubmed:day
17
pubmed:volume
192
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
439-41
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
The effect of neuropeptide Y on voltage-sensitive Ca2+ channels.
pubmed:affiliation
Pharmacology and Therapeutics, Defence Research Establishment Suffield, Alberta, Canada.
pubmed:publicationType
Journal Article, In Vitro