|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0027651,
umls-concept:C0033414,
umls-concept:C0069676,
umls-concept:C0085862,
umls-concept:C0185117,
umls-concept:C0238198,
umls-concept:C1299583,
umls-concept:C1332712,
umls-concept:C1514474,
umls-concept:C1514485,
umls-concept:C1514888,
umls-concept:C1549571,
umls-concept:C1608386,
umls-concept:C1704675,
umls-concept:C2911684
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pubmed:issue |
11
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|
pubmed:dateCreated |
2010-10-7
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|
pubmed:abstractText |
Osteopontin (OPN) is a multifunctional secreted glycophosphoprotein involved in miscellaneous physiologic and pathologic processes and is functionally related to the transmembrane receptor CD44. Although OPN expression has been identified to be associated with poor prognosis in several gastrointestinal malignancies, its expression in gastrointestinal stromal tumor (GIST) has not been thoroughly investigated. This study was designed to evaluate the clinicopathologic significance of OPN expression in patients with resectable GIST.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1534-4681
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3043-52
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pubmed:meshHeading |
pubmed-meshheading:20549562-Aged,
pubmed-meshheading:20549562-Antigens, CD44,
pubmed-meshheading:20549562-Cell Line, Tumor,
pubmed-meshheading:20549562-Cell Proliferation,
pubmed-meshheading:20549562-Female,
pubmed-meshheading:20549562-Gastrointestinal Stromal Tumors,
pubmed-meshheading:20549562-Humans,
pubmed-meshheading:20549562-Intestinal Neoplasms,
pubmed-meshheading:20549562-Male,
pubmed-meshheading:20549562-Middle Aged,
pubmed-meshheading:20549562-Osteopontin,
pubmed-meshheading:20549562-Stomach Neoplasms,
pubmed-meshheading:20549562-Survival Analysis
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|
pubmed:year |
2010
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pubmed:articleTitle |
Osteopontin expression is an independent adverse prognostic factor in resectable gastrointestinal stromal tumor and its interaction with CD44 promotes tumor proliferation.
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pubmed:affiliation |
Institute of Clinical Medicine, National Cheng Kung University, Tainan, Taiwan, Republic of China.
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pubmed:publicationType |
Journal Article
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