Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2010-6-15
pubmed:abstractText
To analyze the frequency of mitochondrial DNA (mtDNA) damage in patients with primary open-angle glaucoma. Oxidative damage plays a major role in glaucoma pathogenesis. Since no environmental risk factor for glaucoma is recognized, we focused our attention on mitochondria, the main endogenous source of reactive oxygen species.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1538-3601
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
128
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
724-30
pubmed:meshHeading
pubmed-meshheading:20547950-Aged, pubmed-meshheading:20547950-Antigens, CD95, pubmed-meshheading:20547950-Case-Control Studies, pubmed-meshheading:20547950-DNA, Mitochondrial, pubmed-meshheading:20547950-DNA Damage, pubmed-meshheading:20547950-DNA Glycosylases, pubmed-meshheading:20547950-Female, pubmed-meshheading:20547950-Gene Dosage, pubmed-meshheading:20547950-Genetic Predisposition to Disease, pubmed-meshheading:20547950-Glaucoma, Open-Angle, pubmed-meshheading:20547950-Glutathione Transferase, pubmed-meshheading:20547950-Humans, pubmed-meshheading:20547950-Intraocular Pressure, pubmed-meshheading:20547950-Male, pubmed-meshheading:20547950-Mitochondrial Diseases, pubmed-meshheading:20547950-Oxidative Stress, pubmed-meshheading:20547950-Polymorphism, Genetic, pubmed-meshheading:20547950-Reactive Oxygen Species, pubmed-meshheading:20547950-Reverse Transcriptase Polymerase Chain Reaction, pubmed-meshheading:20547950-Trabecular Meshwork, pubmed-meshheading:20547950-Trabeculectomy
pubmed:year
2010
pubmed:articleTitle
Mitochondrial damage in the trabecular meshwork of patients with glaucoma.
pubmed:affiliation
Department of Health Sciences, University of Genoa, Genoa, Italy. izzotti@unige.it
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't