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rdf:type |
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lifeskim:mentions |
umls-concept:C0007634,
umls-concept:C0014257,
umls-concept:C0040018,
umls-concept:C0040048,
umls-concept:C0041904,
umls-concept:C0079411,
umls-concept:C0162493,
umls-concept:C0348080,
umls-concept:C0871161,
umls-concept:C1516240,
umls-concept:C1533691
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pubmed:issue |
9
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pubmed:dateCreated |
2010-10-28
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pubmed:abstractText |
Endothelial progenitor cells (EPC) are good candidates for cell-based therapy in cardiovascular diseases. However, concerns have been raised about the potential risks of EPC-based cell therapy, in terms of thrombogenicity particularly in inflammatory conditions, currently observed in such patients. Tissue factor (TF) can trigger coagulation and may support thrombogenicity. TF is also a key receptor in angiogenesis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1538-7836
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pubmed:author |
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pubmed:copyrightInfo |
© 2010 International Society on Thrombosis and Haemostasis.
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pubmed:issnType |
Electronic
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2042-52
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pubmed:meshHeading |
pubmed-meshheading:20546120-Blotting, Western,
pubmed-meshheading:20546120-Cell Proliferation,
pubmed-meshheading:20546120-Coagulants,
pubmed-meshheading:20546120-Endothelium, Vascular,
pubmed-meshheading:20546120-Factor VII,
pubmed-meshheading:20546120-Fetal Blood,
pubmed-meshheading:20546120-Flow Cytometry,
pubmed-meshheading:20546120-Humans,
pubmed-meshheading:20546120-Inflammation,
pubmed-meshheading:20546120-Risk,
pubmed-meshheading:20546120-Thrombin,
pubmed-meshheading:20546120-Thromboplastin,
pubmed-meshheading:20546120-Thrombosis,
pubmed-meshheading:20546120-Tumor Necrosis Factor-alpha,
pubmed-meshheading:20546120-Up-Regulation,
pubmed-meshheading:20546120-Wound Healing
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pubmed:year |
2010
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pubmed:articleTitle |
Tissue factor up-regulation in proinflammatory conditions confers thrombin generation capacity to endothelial colony-forming cells without influencing non-coagulant properties in vitro.
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pubmed:affiliation |
Laboratoire d'Hématologie, CHU Robert Debré and EA-3801, Faculté de Médecine, IFR-53 Interactions Cellules MicroEnvironnement, Université de Reims Champagne-Ardenne, Reims, France.
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pubmed:publicationType |
Journal Article
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