Linked Life Data

20542045

Source:http://linkedlifedata.com/resource/pubmed/id/20542045

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2010-7-12
pubmed:abstractText
Unilateral spatial neglect (USN) is a highly prevalent and disabling consequence of stroke that often responds poorly to existing interventions. Its underlying neural mechanisms are still unclear. Recent work suggests that post-stroke USN may be partly related to a disruption of top-down and bottom-up control of visual attention mediated in part through the midbrain superior colliculi (SC). With mounting evidence from animal and human research, our objectives were: (1) to synthesize the literature implicating the SC in USN; (2) to review the rationale and potential for using eye patching and prism adaptation as USN treatment approaches that recruit SC involvement; and (3) to provide recommendations for research on the potential of therapeutic interventions that involve and/or target the retino-collicular pathway. Given the paucity of human studies, the contribution of the SC in USN, while plausible, remains to be confirmed. Further exploration of the mechanisms involved and their impact on USN in human subjects will help develop theoretically based intervention strategies tailored to USN type.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1873-3514
pubmed:author
pubmed:copyrightInfo
Copyright (c) 2010 Elsevier Ltd. All rights reserved.
pubmed:issnType
Electronic
pubmed:volume
48
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2407-16
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Contribution of the superior colliculi to post-stroke unilateral spatial neglect and recovery.
pubmed:affiliation
Faculty of Medicine, School of Physical and Occupational Therapy, McGill University, 3630 Promenades Sir-William-Osler, Montreal, Quebec H3G 1Y5, Canada. tatiana.ogourtsova@mail.mcgill.ca
pubmed:publicationType
Journal Article, Review