Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1991-7-26
|
pubmed:abstractText |
We performed a prospective, naturalistic study using standardized clinical rating scales to characterize the effect of electroconvulsive therapy (ECT) on mood, cognition, and medical status in late-life depression. Over a 16-month period, 40 patients aged 60 years and over who fulfilled DSM-III criteria for a major depressive episode received a total of 42 ECT courses. Three patients (7%) developed significant medical complications: one had a syncopal episode due to arrhythmia, and two had symptomatic vertebral compression fractures. Confusion was noted during 13 courses (31%) and persisted at discharge in four (10%). More than half the patients were either psychotic or demented on admission, and all but three had been either unresponsive or intolerant to pharmacotherapy. All patients experienced a decrease in their depressive symptoms and more than two thirds were in complete or partial remission at discharge. Patients with psychotic depression experienced a greater improvement than patients with nonpsychotic depression, and patients with organic mental disorders experienced the same improvement as other patients. This study confirms that ECT is a safe and effective treatment of depression in late life.
|
pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0891-9887
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
4
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
3-13
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:2054049-Aged,
pubmed-meshheading:2054049-Aged, 80 and over,
pubmed-meshheading:2054049-Confusion,
pubmed-meshheading:2054049-Depressive Disorder,
pubmed-meshheading:2054049-Electroconvulsive Therapy,
pubmed-meshheading:2054049-Female,
pubmed-meshheading:2054049-Humans,
pubmed-meshheading:2054049-Male,
pubmed-meshheading:2054049-Mental Status Schedule,
pubmed-meshheading:2054049-Middle Aged,
pubmed-meshheading:2054049-Prospective Studies,
pubmed-meshheading:2054049-Psychiatric Status Rating Scales,
pubmed-meshheading:2054049-Psychometrics,
pubmed-meshheading:2054049-Risk Factors
|
pubmed:articleTitle |
A prospective naturalistic study of electroconvulsive therapy in late-life depression.
|
pubmed:affiliation |
Geriatric Health Services, University of Pittsburgh School of Medicine, PA 15213.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|