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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
15
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pubmed:dateCreated |
2010-8-2
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pubmed:abstractText |
The efficacy of angiotensin-converting enzyme (ACE)-inhibitors in stable coronary artery disease (CAD) may be increased by targeting the therapy to those patients most likely to benefit. However, these patients cannot be identified by clinical characteristics. We developed a genetic profile to predict the treatment benefit of ACE-inhibitors exist and to optimize therapy with ACE-inhibitors.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1522-9645
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pubmed:author |
pubmed-author:BertrandMichelM,
pubmed-author:BoersmaEricE,
pubmed-author:BrugtsJasper JanJJ,
pubmed-author:CeconiClaudioC,
pubmed-author:ChalmersJohnJ,
pubmed-author:DanserA H JanAH,
pubmed-author:FerrariRobertoR,
pubmed-author:GenM CMC,
pubmed-author:IsaacsAaronA,
pubmed-author:MacMahonStephenS,
pubmed-author:NinomiyaToshiharuT,
pubmed-author:RemmeWillemW,
pubmed-author:SimoonsMaarten LML,
pubmed-author:UitterlindenAndre GAG,
pubmed-author:WittemanJacqueline C MJC,
pubmed-author:de MaatMoniek P MMP,
pubmed-author:van DuijnCock MCM
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pubmed:issnType |
Electronic
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1854-64
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pubmed:meshHeading |
pubmed-meshheading:20538738-Angiotensin-Converting Enzyme Inhibitors,
pubmed-meshheading:20538738-Coronary Artery Disease,
pubmed-meshheading:20538738-Female,
pubmed-meshheading:20538738-Gene Frequency,
pubmed-meshheading:20538738-Genotype,
pubmed-meshheading:20538738-Heart Arrest,
pubmed-meshheading:20538738-Humans,
pubmed-meshheading:20538738-Kallikrein-Kinin System,
pubmed-meshheading:20538738-Male,
pubmed-meshheading:20538738-Middle Aged,
pubmed-meshheading:20538738-Myocardial Infarction,
pubmed-meshheading:20538738-Perindopril,
pubmed-meshheading:20538738-Pharmacogenetics,
pubmed-meshheading:20538738-Polymorphism, Single Nucleotide,
pubmed-meshheading:20538738-Receptor, Angiotensin, Type 1,
pubmed-meshheading:20538738-Receptor, Bradykinin B1,
pubmed-meshheading:20538738-Renin-Angiotensin System
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pubmed:year |
2010
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pubmed:articleTitle |
Genetic determinants of treatment benefit of the angiotensin-converting enzyme-inhibitor perindopril in patients with stable coronary artery disease.
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pubmed:affiliation |
Department of Cardiology, Erasmus MC, Thoraxcenter, 's Gravendijkwal 230, Rotterdam, The Netherlands. j.brugts@erasmusmc.nl
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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