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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1991-7-23
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pubmed:abstractText |
Mice in experimental delay of implantation were injected intravenously with 75 micrograms.g-1 body weight of lead chloride, corresponding to a dose of lead of about 56 micrograms.g-1 body weight. Delay of implantation was obtained by ovariectomy 3 days after mating followed by a depot dose of progesterone every fifth day. Electron microscopy showed that the uterine lumen, which was closed in control mice, was opened in lead-injected mice. This morphology suggested that lead caused an increase in uterine secretion. X-ray microanalysis of pyroantimonate precipitates in the uterine epithelium of injected mice demonstrated lead in the precipitates, suggesting that lead could have a direct effect on the function of the uterine epithelium and that lead also could be secreted into the uterine lumen and affect the blastocysts.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0340-5761
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
65
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
239-43
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2053850-Animals,
pubmed-meshheading:2053850-Electron Probe Microanalysis,
pubmed-meshheading:2053850-Embryo Implantation, Delayed,
pubmed-meshheading:2053850-Epithelium,
pubmed-meshheading:2053850-Female,
pubmed-meshheading:2053850-Lead,
pubmed-meshheading:2053850-Mice,
pubmed-meshheading:2053850-Microscopy, Electron,
pubmed-meshheading:2053850-Uterus
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pubmed:year |
1991
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pubmed:articleTitle |
Electron microscopy and X-ray microanalyses of uterine epithelium from lead-injected mice in an experimental delay of implantation.
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pubmed:affiliation |
Department of Human Anatomy, Biomedical Centre, Uppsala, Sweden.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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