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rdf:type |
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lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0185117,
umls-concept:C0205082,
umls-concept:C0220905,
umls-concept:C0341305,
umls-concept:C0376315,
umls-concept:C0392756,
umls-concept:C0542341,
umls-concept:C1416467,
umls-concept:C1833334,
umls-concept:C2911684
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pubmed:issue |
3
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pubmed:dateCreated |
2010-8-30
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pubmed:abstractText |
Little is known about the pathophysiology of early onset forms of autoimmune enteropathy (AIE). AIE has been associated with mutations in FOXP3-a transcription factor that controls regulatory T-cell development and function. We analyzed the molecular basis of neonatal or early postnatal AIE using clinical, genetic, and functional immunological studies.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1528-0012
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pubmed:author |
pubmed-author:BegueBernadetteB,
pubmed-author:BiverArmandA,
pubmed-author:BretonAnneA,
pubmed-author:CasanovaJean-LaurentJL,
pubmed-author:Cerf-BensussanNadineN,
pubmed-author:FischerAlainA,
pubmed-author:GouletOlivierO,
pubmed-author:HermineOlivierO,
pubmed-author:MoesNicoletteN,
pubmed-author:NevenBénédicteB,
pubmed-author:OchsHans DHD,
pubmed-author:PateyNatachaN,
pubmed-author:PicardCapucineC,
pubmed-author:PiloquetHuguesH,
pubmed-author:Rieux-LaucatFrédéricF,
pubmed-author:RingsEdmond HhmEH,
pubmed-author:RuemmeleCorinneC,
pubmed-author:RuemmeleFrank MFM,
pubmed-author:StolzenbergMarie-ClaudeMC,
pubmed-author:TorgersonTroy TTT,
pubmed-author:VerdierJulienJ
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pubmed:copyrightInfo |
Copyright © 2010 AGA Institute. Published by Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
139
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
770-8
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pubmed:meshHeading |
pubmed-meshheading:20537998-Age of Onset,
pubmed-meshheading:20537998-Autoimmune Diseases,
pubmed-meshheading:20537998-CD4 Lymphocyte Count,
pubmed-meshheading:20537998-Case-Control Studies,
pubmed-meshheading:20537998-Cells, Cultured,
pubmed-meshheading:20537998-Child,
pubmed-meshheading:20537998-Child, Preschool,
pubmed-meshheading:20537998-Coculture Techniques,
pubmed-meshheading:20537998-Down-Regulation,
pubmed-meshheading:20537998-Female,
pubmed-meshheading:20537998-Flow Cytometry,
pubmed-meshheading:20537998-Forkhead Transcription Factors,
pubmed-meshheading:20537998-Humans,
pubmed-meshheading:20537998-Immunosuppressive Agents,
pubmed-meshheading:20537998-Infant,
pubmed-meshheading:20537998-Infant, Newborn,
pubmed-meshheading:20537998-Interleukin-2 Receptor alpha Subunit,
pubmed-meshheading:20537998-Intestinal Diseases,
pubmed-meshheading:20537998-Male,
pubmed-meshheading:20537998-Microscopy, Confocal,
pubmed-meshheading:20537998-Mutation,
pubmed-meshheading:20537998-Open Reading Frames,
pubmed-meshheading:20537998-Parenteral Nutrition, Total,
pubmed-meshheading:20537998-Promoter Regions, Genetic,
pubmed-meshheading:20537998-RNA, Messenger,
pubmed-meshheading:20537998-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:20537998-Severity of Illness Index,
pubmed-meshheading:20537998-T-Lymphocytes, Regulatory,
pubmed-meshheading:20537998-Treatment Outcome
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pubmed:year |
2010
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pubmed:articleTitle |
Reduced expression of FOXP3 and regulatory T-cell function in severe forms of early-onset autoimmune enteropathy.
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pubmed:affiliation |
Université Paris Descartes, Paris, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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