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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2010-7-19
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pubmed:abstractText |
The insulin receptor-related receptor (IRR) is an orphan receptor belonging to the insulin receptor (IR) family. Despite its unknown function, the specific tissue expression and the high sequence homology with the IR and the insulin-like growth factor 1 receptor (IGF1R) suggest a biological role in beta-cells.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Insulin,
http://linkedlifedata.com/resource/pubmed/chemical/Macrophage Colony-Stimulating Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinase 1,
http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinase 3,
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-akt,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Insulin,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Macrophage...,
http://linkedlifedata.com/resource/pubmed/chemical/Somatomedins,
http://linkedlifedata.com/resource/pubmed/chemical/Tyrosine,
http://linkedlifedata.com/resource/pubmed/chemical/insulin receptor-related receptor
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1744-4160
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
116
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
128-36
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:20536329-Animals,
pubmed-meshheading:20536329-Apoptosis,
pubmed-meshheading:20536329-Cell Line, Tumor,
pubmed-meshheading:20536329-Cell Proliferation,
pubmed-meshheading:20536329-Gene Expression Regulation,
pubmed-meshheading:20536329-Humans,
pubmed-meshheading:20536329-Insulin,
pubmed-meshheading:20536329-Insulin-Secreting Cells,
pubmed-meshheading:20536329-Macrophage Colony-Stimulating Factor,
pubmed-meshheading:20536329-Mitogen-Activated Protein Kinase 1,
pubmed-meshheading:20536329-Mitogen-Activated Protein Kinase 3,
pubmed-meshheading:20536329-Phosphorylation,
pubmed-meshheading:20536329-Proto-Oncogene Proteins c-akt,
pubmed-meshheading:20536329-Rats,
pubmed-meshheading:20536329-Receptor, Insulin,
pubmed-meshheading:20536329-Receptor, Macrophage Colony-Stimulating Factor,
pubmed-meshheading:20536329-Signal Transduction,
pubmed-meshheading:20536329-Somatomedins,
pubmed-meshheading:20536329-Tyrosine
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pubmed:year |
2010
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pubmed:articleTitle |
Activation of Erk1/2 phosphorylation but not of Akt/Pkb through an inducible CSF1R/IRR-receptor construct in INS-1E beta-cells.
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pubmed:affiliation |
Hospital for Children and Adolescents, University of Leipzig, Leipzig, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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