Linked Life Data

20536325

Source:http://linkedlifedata.com/resource/pubmed/id/20536325

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2010-6-11
pubmed:abstractText
Over the past few decades with the rapid advances in embryo and embryonic stem cell manipulation techniques, transgenic mouse models have emerged as a powerful tool for the study of gene function and complex diseases including male infertility. In this review we give a brief history of the development of tools for the production of transgenic mouse models. This spans the advances from early pronuclear injection to the use of targeted embryonic stem cells to produce gene targeted, conditional, and inducible knockout mouse models. Lastly we provide a few examples to illustrate the utility of mouse models in the study of male infertility.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1939-6376
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
56
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
260-73
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
The use of transgenic mouse models in the study of male infertility.
pubmed:affiliation
Transgenic and Gene Targeting Mouse Core, University of Utah School of Medicine, Salt Lake City, Utah 84108, USA.
pubmed:publicationType
Journal Article, Review