Source:http://linkedlifedata.com/resource/pubmed/id/20535852
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
2010-6-9
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pubmed:abstractText |
The endolymphatic calcium concentration [Ca2+] is essential for acoustic transduction. This study investigated the changes in cochlear function caused by vestibular labyrinth destruction in the acute phase by measurement of the endocochlear potential and endolymphatic [Ca2+].Hartley guinea pigs underwent lateral semicircular canal transection with suctioning of the perilymph, ampullectomy, or destruction of the lateral part of the vestibule. The endocochlear potential and endolymphatic [Ca2+] showed mild change after lateral semicircular canal transection with suctioning or ampullectomy. However, the endocochlear potential decreased drastically and permanently, and the endolymphatic [Ca2+] elevated suddenly but finally normalized after vestibulotomy. Elevated endolymphatic [Ca2+] is important in the disturbance of the mechanism of cochlear function caused by vestibular labyrinth destruction.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1473-558X
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
23
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
651-5
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pubmed:meshHeading |
pubmed-meshheading:20535852-Animals,
pubmed-meshheading:20535852-Calcium,
pubmed-meshheading:20535852-Cochlea,
pubmed-meshheading:20535852-Endolymph,
pubmed-meshheading:20535852-Guinea Pigs,
pubmed-meshheading:20535852-Hair Cells, Ampulla,
pubmed-meshheading:20535852-Male,
pubmed-meshheading:20535852-Membrane Potentials,
pubmed-meshheading:20535852-Perilymph,
pubmed-meshheading:20535852-Semicircular Canals,
pubmed-meshheading:20535852-Time Factors,
pubmed-meshheading:20535852-Vestibule, Labyrinth
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pubmed:year |
2010
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pubmed:articleTitle |
Calcium concentration in cochlear endolymph after vestibular labyrinth injury.
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pubmed:affiliation |
Department of Otolaryngology-Head and Neck Surgery, Tohoku University School of Medicine, Sendai 980-8574, Japan. ryoukich@hotmail.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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