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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1991-7-24
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pubmed:abstractText |
Aztreonam, the first monocyclic beta-lactam antibiotic with pure anti-Gram-negative activity, combined with flucloxacillin, a penicillinase resistant penicillin, was given as empirical treatment of 53 serious infections in very elderly people. Eighteen of the cases had positive blood cultures and 11 had a clinical picture of sepsis without positive blood cultures: Of 49 evaluable infections, 45 (92%) were cured. In 40% of the infections, antibiotic treatment could be narrowed after 72 hours to one antibiotic. Diarrhoea, mostly transitory, was the only side-effect. Aztreonam-flucloxacillin combination is a safe and effective empirical treatment regimen for serious infections in very elderly patients.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0002-0729
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
135-9
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:2053504-Aged,
pubmed-meshheading:2053504-Aged, 80 and over,
pubmed-meshheading:2053504-Aztreonam,
pubmed-meshheading:2053504-Bacterial Infections,
pubmed-meshheading:2053504-Drug Evaluation,
pubmed-meshheading:2053504-Drug Therapy, Combination,
pubmed-meshheading:2053504-Female,
pubmed-meshheading:2053504-Floxacillin,
pubmed-meshheading:2053504-Humans,
pubmed-meshheading:2053504-Injections, Intravenous,
pubmed-meshheading:2053504-Male
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pubmed:year |
1991
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pubmed:articleTitle |
Aztreonam-flucloxacillin double beta-lactam treatment as empirical therapy of serious infections in very elderly patients.
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pubmed:affiliation |
Department of Internal Medicine, University Hospital Gasthuisberg, Leuven, Belgium.
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pubmed:publicationType |
Journal Article
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