20531417

Source:http://linkedlifedata.com/resource/pubmed/id/20531417

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0007102, umls-concept:C0334227, umls-concept:C0671771, umls-concept:C1514485
pubmed:issue	12
pubmed:dateCreated	2010-6-9
pubmed:abstractText	Pregnane X receptor (PXR) is a nuclear receptor that regulates the metabolism and disposition of various xenobiotics and endobioitics. We investigated a novel PXR function in regulating colon tumourigenesis in this study.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/ES09859
pubmed:commentsCorrections	http://linkedlifedata.com/resource/pubmed/commentcorrection/20531417-14657421, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531417-15236169, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531417-15825116, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531417-15899785, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531417-16472590, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531417-16608838, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531417-16841097, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531417-17008321, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531417-17170021, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531417-17828778, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531417-18167061, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531417-18381355, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531417-18765524, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531417-19123943, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531417-19144646, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531417-19240808, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531417-9727070, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531417-9784494
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0370635
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/CDKN1A protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Cyclin-Dependent Kinase Inhibitor..., http://linkedlifedata.com/resource/pubmed/chemical/E2F1 Transcription Factor, http://linkedlifedata.com/resource/pubmed/chemical/E2F1 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Steroid, http://linkedlifedata.com/resource/pubmed/chemical/Tumor Suppressor Proteins, http://linkedlifedata.com/resource/pubmed/chemical/pregnane X receptor
pubmed:status	MEDLINE
pubmed:month	Jun
pubmed:issn	1532-1827
pubmed:author	pubmed-author:ChenGG, pubmed-author:EagletonNN, pubmed-author:LITT, pubmed-author:LaffinsBB, pubmed-author:OuyangNN, pubmed-author:TianYY, pubmed-author:XieYY, pubmed-author:YaoHH, pubmed-author:ZhouBB
pubmed:issnType	Electronic
pubmed:day	8
pubmed:volume	102
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1753-61
pubmed:dateRevised	2011-7-28
pubmed:meshHeading	pubmed-meshheading:20531417-Animals, pubmed-meshheading:20531417-Cell Proliferation, pubmed-meshheading:20531417-Colonic Neoplasms, pubmed-meshheading:20531417-Cyclin-Dependent Kinase Inhibitor p21, pubmed-meshheading:20531417-E2F1 Transcription Factor, pubmed-meshheading:20531417-HT29 Cells, pubmed-meshheading:20531417-Hep G2 Cells, pubmed-meshheading:20531417-Humans, pubmed-meshheading:20531417-Mice, pubmed-meshheading:20531417-Mice, Nude, pubmed-meshheading:20531417-Neoplasm Transplantation, pubmed-meshheading:20531417-Receptors, Steroid, pubmed-meshheading:20531417-Transfection, pubmed-meshheading:20531417-Tumor Suppressor Proteins
pubmed:year	2010
pubmed:articleTitle	Pregnane X receptor suppresses proliferation and tumourigenicity of colon cancer cells.
pubmed:affiliation	Department of Veterinary Physiology and Pharmacology, Texas A&M University, College Station, TX 77843, USA.
pubmed:publicationType	Journal Article, Research Support, N.I.H., Extramural