20531415

Source:http://linkedlifedata.com/resource/pubmed/id/20531415

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0087111, umls-concept:C0441655, umls-concept:C0812241, umls-concept:C0870509, umls-concept:C1513095, umls-concept:C1999216, umls-concept:C2004454
pubmed:issue	12
pubmed:dateCreated	2010-6-9
pubmed:abstractText	Resistance to BRAF inhibitors is an emerging problem in the melanoma field. Strategies to prevent and overcome resistance are urgently required.
pubmed:commentsCorrections	http://linkedlifedata.com/resource/pubmed/commentcorrection/20531415-12068308, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531415-12594806, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531415-14500344, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531415-15059882, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531415-15208680, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531415-15520807, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531415-15549090, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531415-15735667, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531415-15781657, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531415-15855653, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531415-15967111, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531415-16007203, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531415-16731745, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531415-17145850, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531415-17210691, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531415-17210701, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531415-17245336, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531415-17546049, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531415-18172275, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531415-18458053, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531415-18559533, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531415-18715233, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531415-19156138, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531415-19726761, http://linkedlifedata.com/resource/pubmed/commentcorrection/20531415-19726788
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0370635
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/BRAF protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Extracellular Signal-Regulated MAP..., http://linkedlifedata.com/resource/pubmed/chemical/Indoles, http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinases, http://linkedlifedata.com/resource/pubmed/chemical/PLX 4720, http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins B-raf, http://linkedlifedata.com/resource/pubmed/chemical/Sulfonamides
pubmed:status	MEDLINE
pubmed:month	Jun
pubmed:issn	1532-1827
pubmed:author	pubmed-author:CantiniL PLP, pubmed-author:FedorenkoI VIV, pubmed-author:FlahertyK TKT, pubmed-author:HallMM, pubmed-author:MessinaJ LJL, pubmed-author:MunkoA CAC, pubmed-author:ParaisoK H TKH, pubmed-author:SmalleyK S MKS, pubmed-author:SondakV KVK
pubmed:issnType	Electronic
pubmed:day	8
pubmed:volume	102
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1724-30
pubmed:dateRevised	2011-7-28
pubmed:meshHeading	pubmed-meshheading:20531415-Apoptosis, pubmed-meshheading:20531415-Cell Line, Tumor, pubmed-meshheading:20531415-Dose-Response Relationship, Drug, pubmed-meshheading:20531415-Drug Resistance, Neoplasm, pubmed-meshheading:20531415-Extracellular Signal-Regulated MAP Kinases, pubmed-meshheading:20531415-Humans, pubmed-meshheading:20531415-Indoles, pubmed-meshheading:20531415-MAP Kinase Signaling System, pubmed-meshheading:20531415-Melanoma, pubmed-meshheading:20531415-Mitogen-Activated Protein Kinases, pubmed-meshheading:20531415-Mutation, pubmed-meshheading:20531415-Proto-Oncogene Proteins B-raf, pubmed-meshheading:20531415-Signal Transduction, pubmed-meshheading:20531415-Sulfonamides, pubmed-meshheading:20531415-Time Factors
pubmed:year	2010
pubmed:articleTitle	Recovery of phospho-ERK activity allows melanoma cells to escape from BRAF inhibitor therapy.
pubmed:affiliation	Department of Molecular Oncology, The Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL 33612, USA.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't