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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2010-6-9
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pubmed:abstractText |
Various factors are involved in the pathogenesis of schizophrenia. Accumulation of advanced glycation end products, including pentosidine, results from carbonyl stress, a state featuring an increase in reactive carbonyl compounds (RCOs) and their attendant protein modifications. Vitamin B(6) is known to detoxify RCOs, including advanced glycation end products. Glyoxalase I (GLO1) is one of the enzymes required for the cellular detoxification of RCOs.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1538-3636
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pubmed:author |
pubmed-author:AikawaYuuzouY,
pubmed-author:AraiMakotoM,
pubmed-author:AraiMayumiM,
pubmed-author:FurukawaAizoA,
pubmed-author:HagaSeiichiS,
pubmed-author:HashimotoKenjiK,
pubmed-author:IchikawaTomoeT,
pubmed-author:ItokawaMasanariM,
pubmed-author:IwayamaYoshimiY,
pubmed-author:IyoMasaomiM,
pubmed-author:IzawaRyosukeR,
pubmed-author:KurodaOsamuO,
pubmed-author:MatsushitaMasaakiM,
pubmed-author:MatsuzawaDaisukeD,
pubmed-author:MiyataToshioT,
pubmed-author:MoriNorioN,
pubmed-author:NakamuraKazuhikoK,
pubmed-author:NiizatoKazuhiroK,
pubmed-author:NishidaAtsushiA,
pubmed-author:NoharaIzumiI,
pubmed-author:ObataNanakoN,
pubmed-author:OhnishiTetsuoT,
pubmed-author:OkazakiYujiY,
pubmed-author:SoraIchiroI,
pubmed-author:TanakaYokoY,
pubmed-author:ToyotaTomokoT,
pubmed-author:UjikeHiroshiH,
pubmed-author:YoshikawaTakeoT,
pubmed-author:YuzawaHirokoH
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pubmed:issnType |
Electronic
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pubmed:volume |
67
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
589-97
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pubmed:meshHeading |
pubmed-meshheading:20530008-Arginine,
pubmed-meshheading:20530008-Biological Markers,
pubmed-meshheading:20530008-Chromatography, High Pressure Liquid,
pubmed-meshheading:20530008-Female,
pubmed-meshheading:20530008-Glycosylation End Products, Advanced,
pubmed-meshheading:20530008-Humans,
pubmed-meshheading:20530008-Lactoylglutathione Lyase,
pubmed-meshheading:20530008-Lysine,
pubmed-meshheading:20530008-Male,
pubmed-meshheading:20530008-Middle Aged,
pubmed-meshheading:20530008-Oxidative Stress,
pubmed-meshheading:20530008-Schizophrenia,
pubmed-meshheading:20530008-Vitamin B 6
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pubmed:year |
2010
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pubmed:articleTitle |
Enhanced carbonyl stress in a subpopulation of schizophrenia.
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pubmed:affiliation |
Project for Schizophrenia Research, Tokyo Institute of Psychiatry, 2-1-8 Kamikitazawa, Setagaya, Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Multicenter Study
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