Source:http://linkedlifedata.com/resource/pubmed/id/20529763
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
2010-10-4
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pubmed:abstractText |
Organophosphate pesticides act as cholinesterase inhibitors. For those with agricultural exposure to these chemicals, risk of potential exposure-related health effects may be modified by genetic variability in cholinesterase metabolism. Cholinesterase activity is a useful, indirect measurement of pesticide exposure, especially in high-risk individuals such as farmworkers. To understand fully the links between pesticide exposure and potential human disease, analyses must be able to consider genetic variability in pesticide metabolism.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1552-9924
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pubmed:author |
pubmed-author:ArcuryThomas ATA,
pubmed-author:ChenHaiyingH,
pubmed-author:GrzywaczJoseph GJG,
pubmed-author:HowardTimothy DTD,
pubmed-author:HsuFang-ChiFC,
pubmed-author:PadillaStephanieS,
pubmed-author:QuandtSara ASA,
pubmed-author:VallejosQuirina MQM,
pubmed-author:WhalleyLara ELE,
pubmed-author:YaiD IDI
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pubmed:issnType |
Electronic
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pubmed:volume |
118
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1395-9
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pubmed:meshHeading |
pubmed-meshheading:20529763-Adolescent,
pubmed-meshheading:20529763-Adult,
pubmed-meshheading:20529763-Agriculture,
pubmed-meshheading:20529763-Butyrylcholinesterase,
pubmed-meshheading:20529763-Female,
pubmed-meshheading:20529763-Humans,
pubmed-meshheading:20529763-Male,
pubmed-meshheading:20529763-Occupational Exposure,
pubmed-meshheading:20529763-Organophosphorus Compounds,
pubmed-meshheading:20529763-Pesticides,
pubmed-meshheading:20529763-Polymorphism, Single Nucleotide
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pubmed:year |
2010
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pubmed:articleTitle |
Evaluation of candidate genes for cholinesterase activity in farmworkers exposed to organophosphorus pesticides: association of single nucleotide polymorphisms in BCHE.
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pubmed:affiliation |
Center for Genomics and Personalized Medicine Research, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA. tdhoward@wfubmc.edu
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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