rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2010-7-12
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pubmed:abstractText |
To control multidrug resistant tuberculosis (MDR-TB), the drug susceptibility profile is needed to guide therapy. Classical drug susceptibility testing (DST) may take up to 2 to 4 months. The GenoType MTBDRplus test is a commercially available line-probe assay that rapidly detects Mycobacterium tuberculosis (MTB) complex, as well as the most common mutations associated with rifampin and isoniazid resistance.We assessed sensitivity and specificity of the assay by using a geographically representative set of MTB isolates from the South of Vietnam.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2334
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pubmed:author |
pubmed-author:BuuTran NTN,
pubmed-author:CawsMaxineM,
pubmed-author:CobelensFrank G JFG,
pubmed-author:DungNguyen HNH,
pubmed-author:HangPham TPT,
pubmed-author:HuyenMai N TMN,
pubmed-author:KremerKristinK,
pubmed-author:LanNguyen T NNT,
pubmed-author:O'BrienRichardR,
pubmed-author:SyDinh NDN,
pubmed-author:TiemersmaEdine WEW,
pubmed-author:van SoolingenDickD
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pubmed:issnType |
Electronic
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
149
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pubmed:dateRevised |
2010-9-30
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pubmed:meshHeading |
pubmed-meshheading:20525271-Antitubercular Agents,
pubmed-meshheading:20525271-DNA, Bacterial,
pubmed-meshheading:20525271-Drug Resistance, Multiple, Bacterial,
pubmed-meshheading:20525271-Genotype,
pubmed-meshheading:20525271-Humans,
pubmed-meshheading:20525271-Isoniazid,
pubmed-meshheading:20525271-Microbial Sensitivity Tests,
pubmed-meshheading:20525271-Mycobacterium tuberculosis,
pubmed-meshheading:20525271-Predictive Value of Tests,
pubmed-meshheading:20525271-Rifampin,
pubmed-meshheading:20525271-Sensitivity and Specificity,
pubmed-meshheading:20525271-Tuberculosis, Multidrug-Resistant,
pubmed-meshheading:20525271-Vietnam
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pubmed:year |
2010
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pubmed:articleTitle |
Validation of the GenoType MTBDRplus assay for diagnosis of multidrug resistant tuberculosis in South Vietnam.
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pubmed:affiliation |
KNCV Tuberculosis Foundation, PO Box 146, 2501CC The Hague, The Netherlands.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Validation Studies
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