Source:http://linkedlifedata.com/resource/pubmed/id/20525146
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
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| pubmed:dateCreated |
2010-6-7
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| pubmed:abstractText |
: A 59-year-old man was admitted to the hospital with pulmonary infiltration, fever, erythema, and eosinophilia. Two weeks before admission, he received amoxicillin, acetaminophen, and shoseiryu-to (a Japanese herbal medicine) for a common cold. Bronchoalveolar lavage was performed, and an increased number of eosinophils was recovered. Transbronchial biopsy specimens showed granuloma and interstitial thickening with eosinophils and lymphocytes. Drug-induced eosinophilic pneumonia was suspected, so all drugs were discontinued. The symptoms and infiltration shadow disappeared. A drug-induced lymphocyte stimulation test (DLST) was positive for acetaminophen but not for amoxicillin. In contrast to the DLST, a provocation test revealed that amoxicillin induced the drug allergy. A very striking observation was the coexistence of pulmonary eosinophilia and granulomatous lung infiltrations. In addition, there was a discrepancy between the DLST and provocation test findings. To our knowledge, there is no previous report of drug-induced eosinophilic pneumonia with a granulomatous reaction.
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| pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/20525146-12403887,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20525146-12592301,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20525146-12738653,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20525146-1446520,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20525146-15062595,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20525146-15230812,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20525146-2273603,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20525146-2950581,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20525146-4465459,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20525146-7357954,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20525146-8000107
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:status |
PubMed-not-MEDLINE
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| pubmed:month |
Jun
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| pubmed:issn |
1710-1492
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| pubmed:author | |
| pubmed:issnType |
Electronic
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| pubmed:day |
15
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| pubmed:volume |
3
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
70-2
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| pubmed:year |
2007
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| pubmed:articleTitle |
Amoxicillin-Induced Eosinophilic Pneumonia with Granulomatous Reaction: Discrepancy between Drug-Induced Lymphocyte Stimulation Test Findings and the Provocation Drug Test.
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| pubmed:affiliation |
Division of Respiratory Disease, Department of Brain and Nerve, Oita University Faculty of Medicine, Yufu-city, Oita, Japan. matsuno@med.oita-u.ac.jp.
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| pubmed:publicationType |
Journal Article
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