Linked Life Data

2052421

Source:http://linkedlifedata.com/resource/pubmed/id/2052421

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1991-7-24
pubmed:abstractText
Human enterotoxigenic Escherichia coli adhere to the brush border of human enterocytes. The mean number of bacteria adhering to one enterocyte (adhesion index) varied from 0.5 to 3.1 when the strains produce adhesins. Different factors related to enterocytes and to bacteria are involved in this variability. The number of bacteria which adhered to enterocytes issued from the same donor varied from from 0 to 12. Moreover the proportion of enterocytes on which several bacteria sticked did not exceed 20%. This variability might be due to the disparity in the maturation of the enterocytes. On the other hand, whatever the adhesion factors considered, the adhesion index varied according to the donors. ETEC strains did not express adhesion when bacteria were grown in a liquid medium but this capacity could be restored after transfer on solid medium. This phenomenon seemed like a phase-variation and appeared to be linked to a 4 to 6 kilobases (kb) plasmid. On the other hand, when the bacteria were grown on agar medium (CFA-agar or Mueller-Hinton agar) two phenotypes of colonies could be observed: large colonies (LC) which were composed of non-adhesive bacteria and small colonies (SC) which were composed of a majority of adhesive bacteria; when the number of subcultures was not too great, a majority of colonies presented the small colonies phenotype. The plasmid content analysis showed the segregation of a high molecular weight plasmid DNA (approximately 100 kb) for the bacteria issued from large colonies phenotype.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0369-8114
pubmed:author
pubmed:issnType
Print
pubmed:volume
39
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
185-90
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
[Factors intervening in the variations of in vitro adhesion power of enterotoxinogenic colibacillus (ETEC) to human enterocytes].
pubmed:affiliation
Faculté de Pharmacie, Service de Bactériologie, Clermont-Ferrand, France.
pubmed:publicationType
Journal Article, English Abstract