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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2010-9-29
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pubmed:abstractText |
Autoimmune target tissues in type 1 diabetes include pancreatic ?-cells and peri-islet Schwann cells (pSC)--the latter active participants or passive bystanders in pre-diabetic autoimmune progression. To distinguish between these alternatives, we sought to suppress pSC autoimmunity by transgenic expression of the negative costimulatory molecule B7-H1 in NOD pSC.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD274,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD80,
http://linkedlifedata.com/resource/pubmed/chemical/CD274 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Cd274 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Glial Fibrillary Acidic Protein,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Peptides
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1939-327X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
59
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2588-96
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:20522597-Animals,
pubmed-meshheading:20522597-Antigens, CD,
pubmed-meshheading:20522597-Antigens, CD274,
pubmed-meshheading:20522597-Antigens, CD80,
pubmed-meshheading:20522597-Dendritic Cells,
pubmed-meshheading:20522597-Diabetes Mellitus, Type 1,
pubmed-meshheading:20522597-Gene Expression,
pubmed-meshheading:20522597-Glial Fibrillary Acidic Protein,
pubmed-meshheading:20522597-Histocytochemistry,
pubmed-meshheading:20522597-Humans,
pubmed-meshheading:20522597-Insulin-Secreting Cells,
pubmed-meshheading:20522597-Islets of Langerhans,
pubmed-meshheading:20522597-Lymphocyte Activation,
pubmed-meshheading:20522597-Membrane Glycoproteins,
pubmed-meshheading:20522597-Mice,
pubmed-meshheading:20522597-Mice, Inbred NOD,
pubmed-meshheading:20522597-Mice, Transgenic,
pubmed-meshheading:20522597-Peptides,
pubmed-meshheading:20522597-Promoter Regions, Genetic,
pubmed-meshheading:20522597-Surface Plasmon Resonance,
pubmed-meshheading:20522597-T-Lymphocytes
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pubmed:year |
2010
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pubmed:articleTitle |
Unexpected acceleration of type 1 diabetes by transgenic expression of B7-H1 in NOD mouse peri-islet glia.
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pubmed:affiliation |
Neuroscience and Mental Health Program, Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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