pubmed-article:20522258 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:20522258 | lifeskim:mentions | umls-concept:C0026336 | lld:lifeskim |
pubmed-article:20522258 | lifeskim:mentions | umls-concept:C1185625 | lld:lifeskim |
pubmed-article:20522258 | lifeskim:mentions | umls-concept:C0031327 | lld:lifeskim |
pubmed-article:20522258 | lifeskim:mentions | umls-concept:C1510411 | lld:lifeskim |
pubmed-article:20522258 | lifeskim:mentions | umls-concept:C0205430 | lld:lifeskim |
pubmed-article:20522258 | pubmed:dateCreated | 2010-6-4 | lld:pubmed |
pubmed-article:20522258 | pubmed:abstractText | To fulfill the model based drug development, the very first step is usually a model establishment from published literatures. Pharmacokinetics model is the central piece of model based drug development. This paper proposed an important approach to transform published non-compartment model pharmacokinetics (PK) parameters into compartment model PK parameters. This meta-analysis was performed with a multivariate nonlinear mixed model. A conditional first-order linearization approach was developed for statistical estimation and inference. | lld:pubmed |
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pubmed-article:20522258 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
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pubmed-article:20522258 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
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pubmed-article:20522258 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20522258 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20522258 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20522258 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20522258 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20522258 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20522258 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20522258 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20522258 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20522258 | pubmed:language | eng | lld:pubmed |
pubmed-article:20522258 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20522258 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:20522258 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:20522258 | pubmed:issn | 1752-0509 | lld:pubmed |
pubmed-article:20522258 | pubmed:author | pubmed-author:WangZhipingZ | lld:pubmed |
pubmed-article:20522258 | pubmed:author | pubmed-author:LiLangL | lld:pubmed |
pubmed-article:20522258 | pubmed:author | pubmed-author:QuinneySara... | lld:pubmed |
pubmed-article:20522258 | pubmed:author | pubmed-author:ZhouJihaoJ | lld:pubmed |
pubmed-article:20522258 | pubmed:author | pubmed-author:KimSeonghoS | lld:pubmed |
pubmed-article:20522258 | pubmed:issnType | Electronic | lld:pubmed |
pubmed-article:20522258 | pubmed:volume | 4 Suppl 1 | lld:pubmed |
pubmed-article:20522258 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:20522258 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:20522258 | pubmed:pagination | S8 | lld:pubmed |
pubmed-article:20522258 | pubmed:dateRevised | 2011-7-20 | lld:pubmed |
pubmed-article:20522258 | pubmed:meshHeading | pubmed-meshheading:20522258... | lld:pubmed |
pubmed-article:20522258 | pubmed:meshHeading | pubmed-meshheading:20522258... | lld:pubmed |
pubmed-article:20522258 | pubmed:meshHeading | pubmed-meshheading:20522258... | lld:pubmed |
pubmed-article:20522258 | pubmed:meshHeading | pubmed-meshheading:20522258... | lld:pubmed |
pubmed-article:20522258 | pubmed:meshHeading | pubmed-meshheading:20522258... | lld:pubmed |
pubmed-article:20522258 | pubmed:year | 2010 | lld:pubmed |
pubmed-article:20522258 | pubmed:articleTitle | Non-compartment model to compartment model pharmacokinetics transformation meta-analysis--a multivariate nonlinear mixed model. | lld:pubmed |
pubmed-article:20522258 | pubmed:affiliation | Division of Biostatistics, Department of Medicine, School of Medicine, Indiana University, Indianapolis, IN 46032, USA. zhipwang@iupui.edu | lld:pubmed |
pubmed-article:20522258 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:20522258 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
pubmed-article:20522258 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
pubmed-article:20522258 | pubmed:publicationType | Meta-Analysis | lld:pubmed |
pubmed-article:20522258 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |