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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2010-6-3
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pubmed:abstractText |
Previous studies have shown that MDM2 SNP309 and p53 codon 72 have modifier effects on germline P53 mutations, but those studies relied on case-only studies with small sample sizes. The impact of MDM4 polymorphism on tumor onset in germline mutation carriers has not previously been studied.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/20520810-10626796,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20520810-11219776,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20520810-11739646,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20520810-12567188,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20520810-12610779,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20520810-12676907,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20520810-15550242,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20520810-16258005,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20520810-1642235,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20520810-16543935,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20520810-16707433,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20520810-18701437,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20520810-1933872,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20520810-19423162,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20520810-19497887,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20520810-19542078,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20520810-19762336,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20520810-3592122,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20520810-3859205,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20520810-7819275,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20520810-9006316,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20520810-9891077
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1932-6203
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pubmed:author |
pubmed-author:AmosChristopher ICI,
pubmed-author:BachinskiLinda LLL,
pubmed-author:ChenWeiW,
pubmed-author:FangShenyingS,
pubmed-author:HanYounghunY,
pubmed-author:KraheRalfR,
pubmed-author:LozanoGuillerminaG,
pubmed-author:PostSean MSM,
pubmed-author:StrongLouise CLC,
pubmed-author:WilsonCharmaine DCD,
pubmed-author:ZhangBailiB
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pubmed:issnType |
Electronic
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e10813
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:20520810-Adolescent,
pubmed-meshheading:20520810-Adult,
pubmed-meshheading:20520810-Codon,
pubmed-meshheading:20520810-Cohort Studies,
pubmed-meshheading:20520810-Female,
pubmed-meshheading:20520810-Genetic Predisposition to Disease,
pubmed-meshheading:20520810-Germ-Line Mutation,
pubmed-meshheading:20520810-Heterozygote,
pubmed-meshheading:20520810-Humans,
pubmed-meshheading:20520810-Incidence,
pubmed-meshheading:20520810-Kaplan-Meier Estimate,
pubmed-meshheading:20520810-Male,
pubmed-meshheading:20520810-Multivariate Analysis,
pubmed-meshheading:20520810-Neoplasms,
pubmed-meshheading:20520810-Nuclear Proteins,
pubmed-meshheading:20520810-Polymorphism, Single Nucleotide,
pubmed-meshheading:20520810-Proto-Oncogene Proteins,
pubmed-meshheading:20520810-Proto-Oncogene Proteins c-mdm2,
pubmed-meshheading:20520810-Tumor Suppressor Protein p53,
pubmed-meshheading:20520810-United States,
pubmed-meshheading:20520810-Young Adult
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pubmed:year |
2010
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pubmed:articleTitle |
Effects of MDM2, MDM4 and TP53 codon 72 polymorphisms on cancer risk in a cohort study of carriers of TP53 germline mutations.
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pubmed:affiliation |
Department of Epidemiology, University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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