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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2010-8-12
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pubmed:abstractText |
Transient receptor potential vanilloid-1 (TRPV1) receptor has been implicated in the mechanism of acid induced inflammation in gastro-esophageal reflux disease (GERD). It has been demonstrated that the increase in nerve growth factor (NGF) and glial derived neurotrophic factor (GDNF) was associated with the increased expression of TRPV1. We aimed to determine whether expression of TRPV1 was increased in severe inflamed human esophagus, and to test the hypothesis whether the expression of TRPV1 was mediated by neurotrophic factors such as NGF and GDNF.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1365-2982
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
971-7, e252
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pubmed:meshHeading |
pubmed-meshheading:20518854-Adult,
pubmed-meshheading:20518854-Aged,
pubmed-meshheading:20518854-Esophagitis, Peptic,
pubmed-meshheading:20518854-Esophagus,
pubmed-meshheading:20518854-Female,
pubmed-meshheading:20518854-Gastroesophageal Reflux,
pubmed-meshheading:20518854-Gene Expression,
pubmed-meshheading:20518854-Glial Cell Line-Derived Neurotrophic Factor,
pubmed-meshheading:20518854-Humans,
pubmed-meshheading:20518854-Immunohistochemistry,
pubmed-meshheading:20518854-Inflammation,
pubmed-meshheading:20518854-Male,
pubmed-meshheading:20518854-Middle Aged,
pubmed-meshheading:20518854-Nerve Growth Factor,
pubmed-meshheading:20518854-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:20518854-TRPV Cation Channels,
pubmed-meshheading:20518854-Up-Regulation
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pubmed:year |
2010
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pubmed:articleTitle |
Evidence for neurotrophic factors associating with TRPV1 gene expression in the inflamed human esophagus.
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pubmed:affiliation |
Institute of Neuroscience, Tzu Chi University, Hualien, Taiwan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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