Linked Life Data

20518556

Source:http://linkedlifedata.com/resource/pubmed/id/20518556

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2010-8-2
pubmed:abstractText
Simultaneous interpenetrating polymer networks (sIPNs) from concurrent copper(I)-catalyzed azide-alkyne cycloaddition "click chemistry" and atom transfer radical polymerization (ATRP) are described. Semi-sIPN of poly(ethylene glycol)/poly(2-hydroxyethyl methacrylate) (semi-PEG/PHEMA-sIPN) was first prepared via simultaneous "click chemistry" and ATRP from a mixture of poly(ethylene glycol)-diazide (N3-PEG-N3, Mn=4000 g/mol), tetrakis(2-propynyloxymethyl)methane (TPOM), ethyl-2-bromobutyrate (EBB), CuBr, pentamethyldiethylenetriamine (PMDETA), and 2-hydroxyethyl methacrylate (HEMA) in dimethylformamide (DMF). Full sIPN of PEG/PHEMA (full-PEG/PHEMA-sIPN) was then prepared via simultaneous "click chemistry" and ATRP from a mixture of N3-PEG-N3 (Mn=4000 g/mol), TPOM, EBB, CuBr, PMDETA, HEMA, and poly(ethylene glycol) diacrylate) (PEGDA, Mn=575) in DMF. Both the semi- and full-sIPNs exhibit a fast gelation rate and high gel yield. The sIPNs also exhibit high swelling ratios and good mechanical and antifouling properties. The morphology and thermal behavior of the sIPNs were studied by scanning electron microscopy (SEM), thermogravimetric analysis (TGA), and differential scanning calorimetry (DSC). These sIPNs could find applications as biomaterials for contact lenses, biomedical materials, artificial organs, and drug delivery systems.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1526-4602
pubmed:author
pubmed:issnType
Electronic
pubmed:day
12
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1810-7
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Interpenetrating network hydrogels via simultaneous "click chemistry" and atom transfer radical polymerization.
pubmed:affiliation
School of Chemistry and Chemical Engineering, Southeast University, Jiangning District, Nanjing, Jiangsu Province, People's Republic of China 211189.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't