Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
48
pubmed:dateCreated
2010-6-2
pubmed:abstractText
Adeno-associated viral (AAV) vectors have emerged in recent years as powerful tools for therapeutic gene transfer. Successes in clinical trials and the discovery of several hundreds of naturally occurring AAV isolates have triggered efforts to understand and manipulate this deceptively simple parvovirus for a myriad of gene therapy applications. Exciting breakthroughs based on directed evolution of novel tissue-specific variants from combinatorial AAV libraries have been reported. Recent approaches driven by the availability of structural information have yielded a new generation of reengineered AAV vectors.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/20515607-12136130, http://linkedlifedata.com/resource/pubmed/commentcorrection/20515607-14512555, http://linkedlifedata.com/resource/pubmed/commentcorrection/20515607-16824801, http://linkedlifedata.com/resource/pubmed/commentcorrection/20515607-16971437, http://linkedlifedata.com/resource/pubmed/commentcorrection/20515607-17162189, http://linkedlifedata.com/resource/pubmed/commentcorrection/20515607-17728238, http://linkedlifedata.com/resource/pubmed/commentcorrection/20515607-18414476, http://linkedlifedata.com/resource/pubmed/commentcorrection/20515607-18511559, http://linkedlifedata.com/resource/pubmed/commentcorrection/20515607-19028373, http://linkedlifedata.com/resource/pubmed/commentcorrection/20515607-19051182, http://linkedlifedata.com/resource/pubmed/commentcorrection/20515607-19052631, http://linkedlifedata.com/resource/pubmed/commentcorrection/20515607-19098898, http://linkedlifedata.com/resource/pubmed/commentcorrection/20515607-19121398, http://linkedlifedata.com/resource/pubmed/commentcorrection/20515607-19133809, http://linkedlifedata.com/resource/pubmed/commentcorrection/20515607-19223863, http://linkedlifedata.com/resource/pubmed/commentcorrection/20515607-19234115, http://linkedlifedata.com/resource/pubmed/commentcorrection/20515607-19237554, http://linkedlifedata.com/resource/pubmed/commentcorrection/20515607-19357785, http://linkedlifedata.com/resource/pubmed/commentcorrection/20515607-19603002, http://linkedlifedata.com/resource/pubmed/commentcorrection/20515607-19727141, http://linkedlifedata.com/resource/pubmed/commentcorrection/20515607-19861950, http://linkedlifedata.com/resource/pubmed/commentcorrection/20515607-19900932, http://linkedlifedata.com/resource/pubmed/commentcorrection/20515607-20037580, http://linkedlifedata.com/resource/pubmed/commentcorrection/20515607-20193635
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1944-7930
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
399-403
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Reengineered AAV vectors: old dog, new tricks.
pubmed:affiliation
Gene Therapy Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. aravind_asokan@med.unc.edu
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural, Research Support, American Recovery and Reinvestment Act