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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2010-9-10
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pubmed:abstractText |
The aim of the present study was to determine the function and the role of the scaffold protein AKAP121, tethering cAMP dependent protein kinase A to the outer wall of mitochondria, in neonatal ventricular myocytes and the heart.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1755-3245
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pubmed:author |
pubmed-author:AvvedimentoVittorio EnricoVE,
pubmed-author:CarangiRosaR,
pubmed-author:ChiarielloMassimoM,
pubmed-author:Del GattoAnnaritaA,
pubmed-author:Di LorenzoEmilioE,
pubmed-author:DonatoGiuseppeG,
pubmed-author:EspositoGiovanniG,
pubmed-author:FelicielloAntonioA,
pubmed-author:GarbiCorradoC,
pubmed-author:GuerrieroRosaliaR,
pubmed-author:IndolfiCiroC,
pubmed-author:PerrinoCinziaC,
pubmed-author:SavianoMicheleM,
pubmed-author:SchiattarellaGabriele GGG,
pubmed-author:ZaccaroLauraL
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
88
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
101-10
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pubmed:meshHeading |
pubmed-meshheading:20511238-A Kinase Anchor Proteins,
pubmed-meshheading:20511238-Animals,
pubmed-meshheading:20511238-Animals, Newborn,
pubmed-meshheading:20511238-Apoptosis,
pubmed-meshheading:20511238-Binding, Competitive,
pubmed-meshheading:20511238-Cell Survival,
pubmed-meshheading:20511238-Cells, Cultured,
pubmed-meshheading:20511238-Cyclic AMP,
pubmed-meshheading:20511238-Disease Models, Animal,
pubmed-meshheading:20511238-Down-Regulation,
pubmed-meshheading:20511238-Hypertrophy, Left Ventricular,
pubmed-meshheading:20511238-Male,
pubmed-meshheading:20511238-Mice,
pubmed-meshheading:20511238-Mice, Inbred C57BL,
pubmed-meshheading:20511238-Mitochondria, Heart,
pubmed-meshheading:20511238-Myocytes, Cardiac,
pubmed-meshheading:20511238-Myocytes, Smooth Muscle,
pubmed-meshheading:20511238-Oxidative Stress,
pubmed-meshheading:20511238-Peptides,
pubmed-meshheading:20511238-Rats,
pubmed-meshheading:20511238-Rats, Wistar,
pubmed-meshheading:20511238-Second Messenger Systems
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pubmed:year |
2010
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pubmed:articleTitle |
AKAP121 downregulation impairs protective cAMP signals, promotes mitochondrial dysfunction, and increases oxidative stress.
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pubmed:affiliation |
Department of Clinical Medicine, Cardiovascular and Immunological Sciences, Federico II University, Naples 80131, Italy. perrino@unina.it
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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