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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2010-7-12
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pubmed:abstractText |
Increasing evidence implicates serine proteinases in pathologic tissue turnover. The aim of this study was to assess the role of the transmembrane serine proteinase matriptase in cartilage destruction in osteoarthritis (OA).
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1529-0131
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pubmed:author |
pubmed-author:CawstonTim ETE,
pubmed-author:ClarkIan MIM,
pubmed-author:DavidsonRose KRK,
pubmed-author:DesiletsAntoineA,
pubmed-author:DonellSimon TST,
pubmed-author:FerrellWilliam RWR,
pubmed-author:KelsoElizabeth BEB,
pubmed-author:LeducRichardR,
pubmed-author:LockhartJohn CJC,
pubmed-author:MilnerJennifer MJM,
pubmed-author:PatelAmitA,
pubmed-author:PlevinRobinR,
pubmed-author:RowanAndrew DAD,
pubmed-author:SwinglerTracey ETE,
pubmed-author:YoungDavid ADA
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pubmed:issnType |
Electronic
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pubmed:volume |
62
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1955-66
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pubmed:meshHeading |
pubmed-meshheading:20506309-Animals,
pubmed-meshheading:20506309-Cartilage, Articular,
pubmed-meshheading:20506309-Cattle,
pubmed-meshheading:20506309-Chondrocytes,
pubmed-meshheading:20506309-Extracellular Matrix,
pubmed-meshheading:20506309-Femoral Neck Fractures,
pubmed-meshheading:20506309-Gene Expression Regulation, Enzymologic,
pubmed-meshheading:20506309-Humans,
pubmed-meshheading:20506309-Matrix Metalloproteinases,
pubmed-meshheading:20506309-Mice,
pubmed-meshheading:20506309-Mice, Inbred C57BL,
pubmed-meshheading:20506309-Mice, Knockout,
pubmed-meshheading:20506309-Osteoarthritis, Hip,
pubmed-meshheading:20506309-Proteinase Inhibitory Proteins, Secretory,
pubmed-meshheading:20506309-Receptor, PAR-2,
pubmed-meshheading:20506309-Serine Endopeptidases
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pubmed:year |
2010
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pubmed:articleTitle |
Matriptase is a novel initiator of cartilage matrix degradation in osteoarthritis.
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pubmed:affiliation |
Newcastle University, Newcastle upon Tyne, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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