rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2010-6-23
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pubmed:abstractText |
Carcinoma ex pleomorphic adenoma is a rare histologic subtype of salivary gland cancer with an overall poor prognosis. Limited histopathologic analyses have shown that some such tumors exhibit significant HER2/neu immunoreactivity, suggesting a potential role for HER2-based therapy. We report here a case of a 58-year old man with metastatic carcinoma ex pleomorphic adenoma who achieved a sustained long term response to combination therapy with trastuzumab and capecitabine.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal,
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal, Humanized,
http://linkedlifedata.com/resource/pubmed/chemical/Deoxycytidine,
http://linkedlifedata.com/resource/pubmed/chemical/Fluorouracil,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, erbB-2,
http://linkedlifedata.com/resource/pubmed/chemical/capecitabine,
http://linkedlifedata.com/resource/pubmed/chemical/trastuzumab
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pubmed:status |
MEDLINE
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pubmed:issn |
1758-3284
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pubmed:author |
|
pubmed:issnType |
Electronic
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pubmed:volume |
2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
12
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:20504363-Adenoma, Pleomorphic,
pubmed-meshheading:20504363-Antibodies, Monoclonal,
pubmed-meshheading:20504363-Antibodies, Monoclonal, Humanized,
pubmed-meshheading:20504363-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:20504363-Deoxycytidine,
pubmed-meshheading:20504363-Fluorouracil,
pubmed-meshheading:20504363-Humans,
pubmed-meshheading:20504363-Male,
pubmed-meshheading:20504363-Middle Aged,
pubmed-meshheading:20504363-Receptor, erbB-2,
pubmed-meshheading:20504363-Salivary Gland Neoplasms
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pubmed:year |
2010
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pubmed:articleTitle |
Sustained response of carcinoma ex pleomorphic adenoma treated with trastuzumab and capecitabine.
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pubmed:affiliation |
Lung and Upper Aerodigestive Cancer Research Group, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, USA.
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pubmed:publicationType |
Journal Article,
Case Reports
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