Source:http://linkedlifedata.com/resource/pubmed/id/20503049
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2010-8-4
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pubmed:abstractText |
Technical developments in both magnetic resonance imaging (MRI) and computed tomography (CT) have helped to reduce scan times and expedited the development of dynamic contrast-enhanced (DCE) imaging techniques. Since the temporal change of the image signal following the administration of a diffusible, extracellular contrast agent (CA) is related to the local blood supply and the extravasation of the CA into the interstitial space, DCE imaging can be used to assess tissue microvasculature and microcirculation. It is the aim of this review to summarize the biophysical and tracer kinetic principles underlying this emerging imaging technique offering great potential for non-invasive characterization of tumour angiogenesis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1619-7089
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
37 Suppl 1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
S30-51
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pubmed:meshHeading |
pubmed-meshheading:20503049-Animals,
pubmed-meshheading:20503049-Contrast Media,
pubmed-meshheading:20503049-Humans,
pubmed-meshheading:20503049-Kinetics,
pubmed-meshheading:20503049-Magnetic Resonance Imaging,
pubmed-meshheading:20503049-Models, Biological,
pubmed-meshheading:20503049-Neoplasms,
pubmed-meshheading:20503049-Neovascularization, Pathologic,
pubmed-meshheading:20503049-Radioactive Tracers,
pubmed-meshheading:20503049-Tomography, X-Ray Computed
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pubmed:year |
2010
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pubmed:articleTitle |
Tracer kinetic modelling of tumour angiogenesis based on dynamic contrast-enhanced CT and MRI measurements.
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pubmed:affiliation |
Department of Medical and Occupational Radiation Protection, Oberschleissheim, Germany. gbrix@bfs.de
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
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