Source:http://linkedlifedata.com/resource/pubmed/id/20500796
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2010-10-29
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pubmed:abstractText |
Filaggrin null mutations associate with atopic eczema and also with asthma when present with eczema. However, while epidermal dysfunction is an important factor in disease pathogenesis, it is unclear how such dysfunction interacts with immune responses to contribute to cutaneous and other inflammatory atopic disease.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1365-2133
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pubmed:author | |
pubmed:copyrightInfo |
© 2010 The Authors. Journal Compilation © 2010 British Association of Dermatologists.
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pubmed:issnType |
Electronic
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pubmed:volume |
163
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
544-9
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pubmed:meshHeading |
pubmed-meshheading:20500796-Adult,
pubmed-meshheading:20500796-CD4-Positive T-Lymphocytes,
pubmed-meshheading:20500796-Eczema,
pubmed-meshheading:20500796-Genetic Predisposition to Disease,
pubmed-meshheading:20500796-HLA Antigens,
pubmed-meshheading:20500796-Humans,
pubmed-meshheading:20500796-Immunity, Cellular,
pubmed-meshheading:20500796-Interleukin-4,
pubmed-meshheading:20500796-Intermediate Filament Proteins,
pubmed-meshheading:20500796-Phenotype,
pubmed-meshheading:20500796-Polymerase Chain Reaction,
pubmed-meshheading:20500796-T-Lymphocytes, Helper-Inducer
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pubmed:year |
2010
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pubmed:articleTitle |
Filaggrin null mutations associate with increased frequencies of allergen-specific CD4+ T-helper 2 cells in patients with atopic eczema.
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pubmed:affiliation |
MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford and NIHR Biomedical Research Centre, OX3 9DS, U.K. tess.mcpherson@imm.ox.ac.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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