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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2010-5-25
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pubmed:abstractText |
Peutz-Jeghers syndrome (PJS) is an autosomal dominant inherited disorder that is characterized by intestinal hamartomatous polyps and mucocutaneous pigmentation. Recently, germline mutations in the LKB1 gene have been reported to underlie PJS. The gene that encodes this serine/threonine kinase is located at chromosome 19p13.3. The aim of this study was to investigate the clinical and genetic characteristics of PJS patients in Taiwan.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0929-6646
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2010 Formosan Medical Association & Elsevier. Published by Elsevier B.V. All rights reserved.
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pubmed:issnType |
Print
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pubmed:volume |
109
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
354-61
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pubmed:meshHeading |
pubmed-meshheading:20497868-Adolescent,
pubmed-meshheading:20497868-Adult,
pubmed-meshheading:20497868-Age of Onset,
pubmed-meshheading:20497868-Aged,
pubmed-meshheading:20497868-Child,
pubmed-meshheading:20497868-Codon,
pubmed-meshheading:20497868-Hospitals, University,
pubmed-meshheading:20497868-Humans,
pubmed-meshheading:20497868-Intestinal Polyps,
pubmed-meshheading:20497868-Intussusception,
pubmed-meshheading:20497868-Middle Aged,
pubmed-meshheading:20497868-Mutation,
pubmed-meshheading:20497868-Mutation, Missense,
pubmed-meshheading:20497868-Peutz-Jeghers Syndrome,
pubmed-meshheading:20497868-Polymorphism, Genetic,
pubmed-meshheading:20497868-Protein-Serine-Threonine Kinases,
pubmed-meshheading:20497868-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:20497868-Sequence Analysis, DNA,
pubmed-meshheading:20497868-Taiwan,
pubmed-meshheading:20497868-Young Adult
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pubmed:year |
2010
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pubmed:articleTitle |
Clinical and genetic analysis of Peutz-Jeghers syndrome patients in Taiwan.
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pubmed:affiliation |
Department of Internal Medicine, Far Eastern Memorial Hospital, Taipei, Taiwan.
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pubmed:publicationType |
Journal Article
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