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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2010-6-22
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pubmed:abstractText |
Intraurethral electrical stimulation (IES) of pudendal afferent nerve fibers can evoke both excitatory and inhibitory bladder reflexes in cats. These pudendovesical reflexes are a potential substrate for restoring bladder function in persons with spinal cord injury or other neurological disorders. However, the complex distribution of pudendal afferent fibers along the lower urinary tract presents a challenge when trying to determine the optimal geometry and position of IES electrodes for evoking these reflexes. This study aimed to determine the optimal intraurethral electrode configuration(s) and locations for selectively activating targeted pudendal afferents to aid future preclinical and clinical investigations.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/20497584-10037378,
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2490
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
11
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pubmed:dateRevised |
2010-9-28
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pubmed:meshHeading |
pubmed-meshheading:20497584-Afferent Pathways,
pubmed-meshheading:20497584-Animals,
pubmed-meshheading:20497584-Cats,
pubmed-meshheading:20497584-Computer Simulation,
pubmed-meshheading:20497584-Electric Stimulation,
pubmed-meshheading:20497584-Electrodes,
pubmed-meshheading:20497584-Finite Element Analysis,
pubmed-meshheading:20497584-Male,
pubmed-meshheading:20497584-Models, Neurological,
pubmed-meshheading:20497584-Urethra
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pubmed:year |
2010
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pubmed:articleTitle |
Finite element modeling and in vivo analysis of electrode configurations for selective stimulation of pudendal afferent fibers.
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pubmed:affiliation |
Department of Biomedical Engineering, Duke University, Box 90281, Durham, NC 27708-0281, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, N.I.H., Extramural
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