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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1991-7-23
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pubmed:abstractText |
The natural history of vaginal intraepithelial neoplasia (VAIN) was studied in 23 patients followed for at least 3 years with no treatment. The mean age of the patients was 41 years of age. A large proportion of the VAIN lesions (50%) were multifocal, and approximately one half of the lesions were associated with concomitant cervical or vulvar intraepithelial neoplasia. Progression to invasive vaginal carcinoma occurred in two (9%) cases, persistence of VAIN occurred in three (13%) cases, and regression of VAIN occurred in 18 (78%) cases. The risk for progression to invasive carcinoma emphasizes the significance of colposcopic examination of the vagina with directed biopsy specimens obtained from all lesions.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0008-543X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
68
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
195-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2049744-Adult,
pubmed-meshheading:2049744-Aged,
pubmed-meshheading:2049744-Carcinoma, Squamous Cell,
pubmed-meshheading:2049744-Colposcopy,
pubmed-meshheading:2049744-Female,
pubmed-meshheading:2049744-Follow-Up Studies,
pubmed-meshheading:2049744-Humans,
pubmed-meshheading:2049744-Middle Aged,
pubmed-meshheading:2049744-Neoplasm Invasiveness,
pubmed-meshheading:2049744-Retrospective Studies,
pubmed-meshheading:2049744-Vaginal Neoplasms,
pubmed-meshheading:2049744-Vaginal Smears
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pubmed:year |
1991
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pubmed:articleTitle |
Natural history of vaginal intraepithelial neoplasia.
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pubmed:affiliation |
Department of Obstetrics and Gynecology, University Central Hospital, Helsinki, Finland.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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