Source:http://linkedlifedata.com/resource/pubmed/id/20496312
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
2010-11-12
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pubmed:abstractText |
Emerging evidence suggests that fetuin-A, a liver-derived glycoprotein, represents an important factor in the pathophysiology of the metabolic syndrome, type 2 diabetes and cardiovascular disease. So far circulating fetuin-A was found to be increased in fatty liver disease, however, the precise mechanisms regulating fetuin-A expression and secretion are largely unknown. Here we assessed serum fetuin-A levels in 14 non-diabetic, obese women (BMI 36.5 ± 1.5 kg/m (2)) before and after a 6-week aerobic exercise program. Despite decreasing waist circumference (from 114.9 ± 3.5 to 112.3 ± 3.2 cm; P = 0.006) and body fat content (from 44.1 ± 1.5% to 43.4 ± 1.5%; P = 0.022) regular exercise 3-times per week over a 6-week period did not affect serum fetuin-A levels (before vs. after: 0.440 ± 0.018 vs. 0.440 ± 0.014 ?g/ml; P = 0.767). Thus, our data provide evidence against a major role of exercise in the regulation of serum fetuin-A levels in non-diabetic obese women.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1439-3646
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pubmed:author | |
pubmed:copyrightInfo |
© Georg Thieme Verlag KG Stuttgart · New York.
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pubmed:issnType |
Electronic
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pubmed:volume |
118
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
754-6
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:20496312-Adiposity,
pubmed-meshheading:20496312-Adult,
pubmed-meshheading:20496312-Blood Proteins,
pubmed-meshheading:20496312-Body Mass Index,
pubmed-meshheading:20496312-Exercise,
pubmed-meshheading:20496312-Female,
pubmed-meshheading:20496312-Humans,
pubmed-meshheading:20496312-Middle Aged,
pubmed-meshheading:20496312-Obesity,
pubmed-meshheading:20496312-Premenopause,
pubmed-meshheading:20496312-Waist Circumference,
pubmed-meshheading:20496312-alpha-2-HS-Glycoprotein
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pubmed:year |
2010
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pubmed:articleTitle |
The effect of 6-weeks of aerobic exercise training on serum fetuin-A levels in non-diabetic obese women.
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pubmed:affiliation |
Interdisciplinary Obesity Center, Kantonsspital St Gallen, Rorschach, Switzerland. bernd.schultes@kssg.ch
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pubmed:publicationType |
Journal Article
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