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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2010-11-24
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pubmed:abstractText |
Animal and clinical studies with plant-produced single-chain variable fragment lymphoma vaccines have demonstrated specific immunogenicity and safety. However, the expression levels of such fragments were highly variable and required complex engineering of the linkers. Moreover, the downstream processing could not be built around standard methods like protein A affinity capture.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1569-8041
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pubmed:author |
pubmed-author:BendandiMM,
pubmed-author:Butler-RansohoffJ-EJE,
pubmed-author:FrödeRR,
pubmed-author:GlebaYY,
pubmed-author:HessKK,
pubmed-author:InogésSS,
pubmed-author:KandziaRR,
pubmed-author:KlimyukVV,
pubmed-author:Lòpez-Dìaz de CerioAA,
pubmed-author:LeonWW,
pubmed-author:MarillonnetSS,
pubmed-author:McCormickAA,
pubmed-author:NickstadtAA,
pubmed-author:SmithG AGA,
pubmed-author:ThiemeFF,
pubmed-author:TuséDD,
pubmed-author:VancanneytGG,
pubmed-author:VillanuevaHH
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pubmed:issnType |
Electronic
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2420-7
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:20494963-Agrobacterium tumefaciens,
pubmed-meshheading:20494963-Animals,
pubmed-meshheading:20494963-Cancer Vaccines,
pubmed-meshheading:20494963-Cloning, Molecular,
pubmed-meshheading:20494963-Efficiency,
pubmed-meshheading:20494963-Gene Expression Regulation, Plant,
pubmed-meshheading:20494963-Humans,
pubmed-meshheading:20494963-Immunoglobulin Idiotypes,
pubmed-meshheading:20494963-Individuality,
pubmed-meshheading:20494963-Lymphoma, Non-Hodgkin,
pubmed-meshheading:20494963-Mice,
pubmed-meshheading:20494963-Mice, Inbred C3H,
pubmed-meshheading:20494963-Plantibodies,
pubmed-meshheading:20494963-Plants, Genetically Modified,
pubmed-meshheading:20494963-Time Factors,
pubmed-meshheading:20494963-Vaccines, Synthetic
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pubmed:year |
2010
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pubmed:articleTitle |
Rapid, high-yield production in plants of individualized idiotype vaccines for non-Hodgkin's lymphoma.
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pubmed:affiliation |
Center for Applied Medical Research, University of Navarra, Pamplona, Spain.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Evaluation Studies
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