| pubmed-article:20494579 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:20494579 | lifeskim:mentions | umls-concept:C0021400 | lld:lifeskim |
| pubmed-article:20494579 | lifeskim:mentions | umls-concept:C0041942 | lld:lifeskim |
| pubmed-article:20494579 | lifeskim:mentions | umls-concept:C0332466 | lld:lifeskim |
| pubmed-article:20494579 | lifeskim:mentions | umls-concept:C0243077 | lld:lifeskim |
| pubmed-article:20494579 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
| pubmed-article:20494579 | lifeskim:mentions | umls-concept:C1880355 | lld:lifeskim |
| pubmed-article:20494579 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
| pubmed-article:20494579 | pubmed:issue | 12 | lld:pubmed |
| pubmed-article:20494579 | pubmed:dateCreated | 2010-6-4 | lld:pubmed |
| pubmed-article:20494579 | pubmed:abstractText | A novel class of HA inhibitors (4a) was identified based on ligand similarity search of known HA inhibitors. Parallel synthesis and further structural modifications resulted in 1-phenyl-cyclopentanecarboxylic acid (4-cyano-phenyl)-methyl-amide 4t as a potent and selective inhibitor to phylogenetic H1 influenza viruses with an EC(50) of 98 nM against H1N1 A/Weiss/43 strain and over 1000-fold selectivity against host MDCK cells. | lld:pubmed |
| pubmed-article:20494579 | pubmed:language | eng | lld:pubmed |
| pubmed-article:20494579 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20494579 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:20494579 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20494579 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20494579 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20494579 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:20494579 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:20494579 | pubmed:issn | 1464-3405 | lld:pubmed |
| pubmed-article:20494579 | pubmed:author | pubmed-author:ChenLiL | lld:pubmed |
| pubmed-article:20494579 | pubmed:author | pubmed-author:LiShaohuaS | lld:pubmed |
| pubmed-article:20494579 | pubmed:author | pubmed-author:ZhuLeiL | lld:pubmed |
| pubmed-article:20494579 | pubmed:author | pubmed-author:TangGuozhiG | lld:pubmed |
| pubmed-article:20494579 | pubmed:author | pubmed-author:LiWentaoW | lld:pubmed |
| pubmed-article:20494579 | pubmed:author | pubmed-author:WangLishaL | lld:pubmed |
| pubmed-article:20494579 | pubmed:author | pubmed-author:WuJim ZJZ | lld:pubmed |
| pubmed-article:20494579 | pubmed:author | pubmed-author:YangWengangW | lld:pubmed |
| pubmed-article:20494579 | pubmed:author | pubmed-author:LinXianfengX | lld:pubmed |
| pubmed-article:20494579 | pubmed:author | pubmed-author:QiuZongxingZ | lld:pubmed |
| pubmed-article:20494579 | pubmed:author | pubmed-author:LiHaodongH | lld:pubmed |
| pubmed-article:20494579 | pubmed:copyrightInfo | Copyright 2010 Elsevier Ltd. All rights reserved. | lld:pubmed |
| pubmed-article:20494579 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:20494579 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:20494579 | pubmed:volume | 20 | lld:pubmed |
| pubmed-article:20494579 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:20494579 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:20494579 | pubmed:pagination | 3507-10 | lld:pubmed |
| pubmed-article:20494579 | pubmed:meshHeading | pubmed-meshheading:20494579... | lld:pubmed |
| pubmed-article:20494579 | pubmed:meshHeading | pubmed-meshheading:20494579... | lld:pubmed |
| pubmed-article:20494579 | pubmed:meshHeading | pubmed-meshheading:20494579... | lld:pubmed |
| pubmed-article:20494579 | pubmed:meshHeading | pubmed-meshheading:20494579... | lld:pubmed |
| pubmed-article:20494579 | pubmed:meshHeading | pubmed-meshheading:20494579... | lld:pubmed |
| pubmed-article:20494579 | pubmed:meshHeading | pubmed-meshheading:20494579... | lld:pubmed |
| pubmed-article:20494579 | pubmed:meshHeading | pubmed-meshheading:20494579... | lld:pubmed |
| pubmed-article:20494579 | pubmed:meshHeading | pubmed-meshheading:20494579... | lld:pubmed |
| pubmed-article:20494579 | pubmed:meshHeading | pubmed-meshheading:20494579... | lld:pubmed |
| pubmed-article:20494579 | pubmed:meshHeading | pubmed-meshheading:20494579... | lld:pubmed |
| pubmed-article:20494579 | pubmed:meshHeading | pubmed-meshheading:20494579... | lld:pubmed |
| pubmed-article:20494579 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:20494579 | pubmed:articleTitle | Discovery of novel 1-phenyl-cycloalkane carbamides as potent and selective influenza fusion inhibitors. | lld:pubmed |
| pubmed-article:20494579 | pubmed:affiliation | Roche R&D Center China, Shanghai, China. gordon.tang@roche.com | lld:pubmed |
| pubmed-article:20494579 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:20494579 | lld:chembl |
