Linked Life Data

20493908

Source:http://linkedlifedata.com/resource/pubmed/id/20493908

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2010-7-26
pubmed:abstractText
Many organisms enter quiescence in response to adverse environmental factors. Here, we show that L1 stage C. elegans entered a quiescent state after 3hours exposure to diacetyl in which movement and growth stopped for hours to days after odorant removal. Entry into quiescence was dependent on neurons affected by the osm-3 mutation, and by AWA neurons. Conversely, AWB/AWC neurons, the guanylyl cyclase ODR-1, and the TRPV-channel subunit OCR-2 inhibited entry into L1 arrest. This quiescent behavior represents an alternative use of olfactory signaling pathways besides approach or avoidance, and is a novel model in which to characterize genes implicated in quiescence.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1872-7549
pubmed:author
pubmed:copyrightInfo
Copyright 2010 Elsevier B.V. All rights reserved.
pubmed:issnType
Electronic
pubmed:day
6
pubmed:volume
214
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
12-7
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
A diacetyl-induced quiescence in young Caenorhabditis elegans.
pubmed:affiliation
Department of Molecular Genetics, University of Toronto, Toronto, M5S 3E1, Canada.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't