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rdf:type |
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lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0026986,
umls-concept:C0087111,
umls-concept:C0185117,
umls-concept:C0392747,
umls-concept:C0441889,
umls-concept:C0443172,
umls-concept:C0796347,
umls-concept:C1144149,
umls-concept:C1419703,
umls-concept:C1521461,
umls-concept:C2911684
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pubmed:issue |
3
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|
pubmed:dateCreated |
2010-8-18
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pubmed:abstractText |
Haploinsufficiency of the ribosomal protein S14 RPS14 gene, located in the common deleted region of chromosome 5q, is a potential causal factor of 5q- syndrome. Lenalidomide elicits high response rates and morphological improvements in myelodysplastic syndrome (MDS) patients with chromosome 5q deletion [del(5q)].
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1600-0609
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pubmed:author |
pubmed-author:AlimenaGiulianaG,
pubmed-author:Aloe SpiritiMaria AMA,
pubmed-author:BrecciaMassimoM,
pubmed-author:CortelezziAgostinoA,
pubmed-author:CuzzolaMariaM,
pubmed-author:D'ErrigoMaria GraziaMG,
pubmed-author:FinelliCarloC,
pubmed-author:GalimbertiSaraS,
pubmed-author:GhioRiccardoR,
pubmed-author:IacopinoPasqualeP,
pubmed-author:LaganàCarmeloC,
pubmed-author:LatagliataRobertoR,
pubmed-author:MorabitoFortunatoF,
pubmed-author:NobileFrancescoF,
pubmed-author:OlivaEsther NEN,
pubmed-author:PoloniAntonellaA,
pubmed-author:RoncoFrancescaF,
pubmed-author:SpecchiaGiorginaG
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pubmed:issnType |
Electronic
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pubmed:volume |
85
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
231-5
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pubmed:meshHeading |
pubmed-meshheading:20491881-Aged,
pubmed-meshheading:20491881-Chromosome Deletion,
pubmed-meshheading:20491881-Chromosomes, Human, Pair 5,
pubmed-meshheading:20491881-Cytogenetic Analysis,
pubmed-meshheading:20491881-Female,
pubmed-meshheading:20491881-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:20491881-Humans,
pubmed-meshheading:20491881-Male,
pubmed-meshheading:20491881-Myelodysplastic Syndromes,
pubmed-meshheading:20491881-Ribosomal Proteins,
pubmed-meshheading:20491881-Risk Factors,
pubmed-meshheading:20491881-Thalidomide,
pubmed-meshheading:20491881-Transcription, Genetic
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pubmed:year |
2010
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pubmed:articleTitle |
Changes in RPS14 expression levels during lenalidomide treatment in Low- and Intermediate-1-risk myelodysplastic syndromes with chromosome 5q deletion.
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pubmed:affiliation |
Hematology Unit, Azienda Ospedaliera Bianchi-Melacrino-Morelli, Reggio Calabria, Italy. estheroliva@hotmail.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Multicenter Study,
Clinical Trial, Phase II
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