20488169

Source:http://linkedlifedata.com/resource/pubmed/id/20488169

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0017431, umls-concept:C0034043, umls-concept:C0205210, umls-concept:C1332829, umls-concept:C1428184, umls-concept:C1533148, umls-concept:C2603343
pubmed:issue	17-18
pubmed:dateCreated	2010-7-12
pubmed:abstractText	Admixture is of great relevance to the clinical application of pharmacogenetics and personalized medicine, but unfortunately these studies have been scarce in Puerto Ricans. Besides, allele frequencies for clinically relevant genetic markers in warfarin response (i.e., CYP2C9 and VKORC1) have not yet been fully characterized in this population. Accordingly, this study is aimed at investigating whether a correlation between overall genetic similarity and CYP2C9 and/or VKORC1 genotypes could be established.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/G12 RR003051-20, http://linkedlifedata.com/resource/pubmed/grant/G12RR-03051
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/1302422
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Anticoagulants, http://linkedlifedata.com/resource/pubmed/chemical/Aryl Hydrocarbon Hydroxylases, http://linkedlifedata.com/resource/pubmed/chemical/CYP2C9 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Mixed Function Oxygenases, http://linkedlifedata.com/resource/pubmed/chemical/Warfarin, http://linkedlifedata.com/resource/pubmed/chemical/vitamin K epoxidase
pubmed:status	MEDLINE
pubmed:month	Sep
pubmed:issn	1873-3492
pubmed:author	pubmed-author:BogaardKaliK, pubmed-author:CadillaCarmen LCL, pubmed-author:CruzIrelys AIA, pubmed-author:DucongeJorgeJ, pubmed-author:GorowskiKrystynaK, pubmed-author:KocherlaMohanM, pubmed-author:MirabalSaraS, pubmed-author:RentaJessica YJY, pubmed-author:RuañoGualbertoG, pubmed-author:SeipRichard LRL, pubmed-author:VillagraDavidD, pubmed-author:WindemuthAndreasA
pubmed:copyrightInfo	Copyright 2010 Elsevier B.V. All rights reserved.
pubmed:issnType	Electronic
pubmed:day	6
pubmed:volume	411
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1306-11
pubmed:dateRevised	2011-9-13
pubmed:meshHeading	pubmed-meshheading:20488169-Anticoagulants, pubmed-meshheading:20488169-Aryl Hydrocarbon Hydroxylases, pubmed-meshheading:20488169-Genotype, pubmed-meshheading:20488169-Humans, pubmed-meshheading:20488169-Mixed Function Oxygenases, pubmed-meshheading:20488169-Pharmacogenetics, pubmed-meshheading:20488169-Puerto Rico, pubmed-meshheading:20488169-Warfarin
pubmed:year	2010
pubmed:articleTitle	CYP2C9 and VKORC1 genotypes in Puerto Ricans: A case for admixture-matching in clinical pharmacogenetic studies.
pubmed:affiliation	Laboratory of Personalized Health, Genomas, Inc., Hartford, CT 06106, USA.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural