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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2010-6-2
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pubmed:abstractText |
To determine the safety and feasibility of combining intratumoral reovirus and radiotherapy in patients with advanced cancer and to assess viral biodistribution, reoviral replication in tumors, and antiviral immune responses.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1078-0432
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pubmed:author |
pubmed-author:AhmedMerinaM,
pubmed-author:BeirneDebbieD,
pubmed-author:CoffeyMattM,
pubmed-author:DebonoJohann SJS,
pubmed-author:HarringtonKevin JKJ,
pubmed-author:HarrisDeanD,
pubmed-author:KarapanagiotouEleni MEM,
pubmed-author:MelcherAlan AAA,
pubmed-author:NewboldKateK,
pubmed-author:NuttingChristopher MCM,
pubmed-author:PandhaHardev SHS,
pubmed-author:PrestwichRobinR,
pubmed-author:RoulstoneVictoriaV,
pubmed-author:ThwayKhinK,
pubmed-author:TwiggerKatie RKR,
pubmed-author:VidalLauraL,
pubmed-author:VileRichard GRG,
pubmed-author:WhiteChristine LCL
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pubmed:copyrightInfo |
Copyright 2010 AACR.
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3067-77
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pubmed:dateRevised |
2011-10-11
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pubmed:meshHeading |
pubmed-meshheading:20484020-Adult,
pubmed-meshheading:20484020-Aged,
pubmed-meshheading:20484020-Antibodies, Viral,
pubmed-meshheading:20484020-Combined Modality Therapy,
pubmed-meshheading:20484020-Female,
pubmed-meshheading:20484020-Humans,
pubmed-meshheading:20484020-Male,
pubmed-meshheading:20484020-Mammalian orthoreovirus 3,
pubmed-meshheading:20484020-Middle Aged,
pubmed-meshheading:20484020-Neoplasms,
pubmed-meshheading:20484020-Oncolytic Virotherapy,
pubmed-meshheading:20484020-Radiotherapy Dosage,
pubmed-meshheading:20484020-Tissue Distribution,
pubmed-meshheading:20484020-Virus Replication,
pubmed-meshheading:20484020-Virus Shedding
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pubmed:year |
2010
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pubmed:articleTitle |
Two-stage phase I dose-escalation study of intratumoral reovirus type 3 dearing and palliative radiotherapy in patients with advanced cancers.
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pubmed:affiliation |
The Institute of Cancer Research, Chester Beatty Laboratories, London, United Kingdom. kevin.harrington@icr.ac.uk
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pubmed:publicationType |
Journal Article,
Clinical Trial, Phase I
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