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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2010-6-10
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pubmed:abstractText |
We have previously demonstrated that BEX2 is differentially expressed in breast tumors and has a significant role in promoting cell survival and growth in breast cancer cells. BEX2 expression protects breast cancer cells against mitochondrial apoptosis and G1 cell cycle arrest. In this study we investigated the transcriptional regulation of BEX2 and feedback mechanisms mediating the cellular function of this gene in breast cancer.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/20482821-10072429,
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1476-4598
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
111
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pubmed:dateRevised |
2010-9-28
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pubmed:meshHeading |
pubmed-meshheading:20482821-Blotting, Western,
pubmed-meshheading:20482821-Breast Neoplasms,
pubmed-meshheading:20482821-Cell Line, Tumor,
pubmed-meshheading:20482821-Chromatin Immunoprecipitation,
pubmed-meshheading:20482821-Enzyme Activation,
pubmed-meshheading:20482821-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:20482821-Female,
pubmed-meshheading:20482821-Fluorescent Antibody Technique,
pubmed-meshheading:20482821-Gene Expression,
pubmed-meshheading:20482821-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:20482821-Gene Knockdown Techniques,
pubmed-meshheading:20482821-Humans,
pubmed-meshheading:20482821-MAP Kinase Kinase 4,
pubmed-meshheading:20482821-Mutagenesis, Site-Directed,
pubmed-meshheading:20482821-Nerve Tissue Proteins,
pubmed-meshheading:20482821-Phosphorylation,
pubmed-meshheading:20482821-Proto-Oncogene Proteins c-jun,
pubmed-meshheading:20482821-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:20482821-Signal Transduction,
pubmed-meshheading:20482821-Transcription Factor RelA
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pubmed:year |
2010
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pubmed:articleTitle |
BEX2 has a functional interplay with c-Jun/JNK and p65/RelA in breast cancer.
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pubmed:affiliation |
The University of Queensland Diamantina Institute, Princess Alexandra Hospital, Brisbane Qld 4102, Australia. a.naderi@uq.edu.au
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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