Linked Life Data

20482502

Source:http://linkedlifedata.com/resource/pubmed/id/20482502

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
20
pubmed:dateCreated
2010-7-20
pubmed:abstractText
Carbohydrates have been revealed to play fundamental roles in diverse biological phenomena, such as being recognition sites and biomarkers. Recently, ample nucleic acid aptamers guided for carbohydrate recognition have already been isolated and characterized through SELEX methodology. This review would like to present and discuss these aptamers toward recognizing various carbohydrate targets: monosaccharides, oligosaccharides, polysaccharides, aminoglycoside antibiotics and glycans from glycoproteins. High affinity carbohydrate aptamers that we reviewed herein might shed light on the development of a tool to augment drug discovery creations.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1873-4286
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2269-78
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Aptamer-based carbohydrate recognition.
pubmed:affiliation
Department of Medicinal Chemistry, School of Pharmacy, Shandong University, Jinan, Shandong, 250012, China.
pubmed:publicationType
Journal Article, Review