Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2010-5-18
pubmed:abstractText
Recently developed optical-resolution photoacoustic microscopy (OR-PAM), which is based on the detection of optical absorption contrast, is complementary to other optical microscopy modalities such as optical confocal microscopy, optical coherence tomography, and multiphoton microscopy. A hybrid optical-mechanical scanning configuration increases the imaging speed of OR-PAM significantly, facilitating many demanding biomedical applications. With a high-pulse-repetition-rate laser, the hybrid-scanning OR-PAM can acquire one-dimensional depth-resolved images (A-lines) at 5 kHz and two-dimensional B-scan images containing 800 A-lines at 6.25 Hz. We demonstrated in vivo in a mouse three-dimensional imaging of the iris vasculature in 128 s for an 800x800x200 data set and of the ear vasculature in 256 s for an 800x1600x200 data set.
pubmed:grant
http://linkedlifedata.com/resource/pubmed/grant/5P60DK02057933, http://linkedlifedata.com/resource/pubmed/grant/EB000712A2S1, http://linkedlifedata.com/resource/pubmed/grant/R01 CA113453901, http://linkedlifedata.com/resource/pubmed/grant/R01 CA134539-01A1, http://linkedlifedata.com/resource/pubmed/grant/R01 CA134539-02, http://linkedlifedata.com/resource/pubmed/grant/R01 CA134539-03, http://linkedlifedata.com/resource/pubmed/grant/R01 EB000712, http://linkedlifedata.com/resource/pubmed/grant/R01 EB000712-06A2S1, http://linkedlifedata.com/resource/pubmed/grant/R01 EB000712-07, http://linkedlifedata.com/resource/pubmed/grant/R01 EB000712-07S2, http://linkedlifedata.com/resource/pubmed/grant/R01 EB00071207S2, http://linkedlifedata.com/resource/pubmed/grant/R01 EB008085, http://linkedlifedata.com/resource/pubmed/grant/R01 EB008085-02, http://linkedlifedata.com/resource/pubmed/grant/U54 CA136398, http://linkedlifedata.com/resource/pubmed/grant/U54 CA136398-02
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1539-4794
pubmed:author
pubmed:issnType
Electronic
pubmed:day
15
pubmed:volume
35
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1521-3
pubmed:dateRevised
2011-1-12
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Hybrid-scanning optical-resolution photoacoustic microscopy for in vivo vasculature imaging.
pubmed:affiliation
Department of Biomedical Engineering, Optical Imaging Lab, Washington University in St. Louis, Campus Box 1097,One Brookings Drive, St. Louis, Missouri 63130-4899, USA.
pubmed:publicationType
Journal Article, Research Support, N.I.H., Extramural