|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
7
|
|
pubmed:dateCreated |
2010-6-28
|
|
pubmed:abstractText |
Although there have been several reports in which central nervous system (CNS) metastases of non-small cell lung cancer (NSCLC) were improved by erlotinib, cerebrospinal fluid (CSF) penetration of erlotinib in such patients has not been reported. We investigated CSF concentrations of erlotinib and its active metabolite OSI-420.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jul
|
|
pubmed:issn |
1556-1380
|
|
pubmed:author |
pubmed-author:FujitaShiroS,
pubmed-author:FukudoMasahideM,
pubmed-author:InuiKen-ichiK,
pubmed-author:IrisaKaoruK,
pubmed-author:KimYoung HakYH,
pubmed-author:MasagoKatsuhiroK,
pubmed-author:MioTadashiT,
pubmed-author:MishimaMichiakiM,
pubmed-author:SakamoriYuichiY,
pubmed-author:TeradaTomohiroT,
pubmed-author:TogashiYosukeY
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
5
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
950-5
|
|
pubmed:meshHeading |
pubmed-meshheading:20479691-Adenocarcinoma,
pubmed-meshheading:20479691-Aged,
pubmed-meshheading:20479691-Aged, 80 and over,
pubmed-meshheading:20479691-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:20479691-Central Nervous System Neoplasms,
pubmed-meshheading:20479691-Female,
pubmed-meshheading:20479691-Humans,
pubmed-meshheading:20479691-Lung Neoplasms,
pubmed-meshheading:20479691-Middle Aged,
pubmed-meshheading:20479691-Mutation,
pubmed-meshheading:20479691-Protein Kinase Inhibitors,
pubmed-meshheading:20479691-Quinazolines,
pubmed-meshheading:20479691-Receptor, Epidermal Growth Factor,
pubmed-meshheading:20479691-Survival Rate,
pubmed-meshheading:20479691-Tissue Distribution,
pubmed-meshheading:20479691-Treatment Outcome
|
|
pubmed:year |
2010
|
|
pubmed:articleTitle |
Cerebrospinal fluid concentration of erlotinib and its active metabolite OSI-420 in patients with central nervous system metastases of non-small cell lung cancer.
|
|
pubmed:affiliation |
Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
|
|
pubmed:publicationType |
Journal Article,
Case Reports
|
